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IDN 5109

Known as: IDN5109, IND5109 
 
National Institutes of Health

Papers overview

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2006
2006
Taxanes, a new class of antitumor drugs, are effective against a large number of human tumors, although there are problems with… Expand
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2005
2005
Starting from 10-deacetylbaccatin III (7), the 2-debenzoyl-2-m-methoxybenzoyl analogs of the newer generation taxoids IDN5109 (3… Expand
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Review
2002
Review
2002
Abstract Paclitaxel (Taxol®) and docetaxel (Taxotère®) are currently two of the most important anticancer drugs in cancer… Expand
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2002
2002
SB-T-1213 and IDN5109 are semisynthetic, orally available taxanes that are up to 400-fold more active than paclitaxel against… Expand
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Review
2002
Review
2002
P-glycoprotein (P-GP)-based multidrug resistance (MDR) and undesirable side effects are significant drawbacks to the clinical use… Expand
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2001
2001
PURPOSE Protein kinase A type I (PKAI) and the epidermal growth factor receptor (EGFR) play a role in neoplastic transformation… Expand
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2000
2000
Abstract Using a model of human cervical cancer (ME-180 cells), the anti-tumour activity of paclitaxel was compared to that of… Expand
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2000
2000
IDN5109 is a new taxane, derived from 14beta-hydroxy-10-deacetylbaccatin III, selected for its lack of cross-resistance in tumor… Expand
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1999
1999
Clinically available taxanes represent one of the most promising class of antitumor agents, despite several problems with their… Expand
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1999
1999
An HPLC assay was developed to determine the paclitaxel analogue 13-(N-tert.-butoxycarbonyl-beta-isobutylisoserinyl)-14-hydroxyb… Expand
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