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IDN 5109

Known as: IDN5109, IND5109 
National Institutes of Health

Papers overview

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2005
2005
Starting from 10-deacetylbaccatin III (7), the 2-debenzoyl-2-m-methoxybenzoyl analogs of the newer generation taxoids IDN5109 (3… Expand
Review
2002
Review
2002
Abstract Paclitaxel (Taxol®) and docetaxel (Taxotère®) are currently two of the most important anticancer drugs in cancer… Expand
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2002
2002
SB-T-1213 and IDN5109 are semisynthetic, orally available taxanes that are up to 400-fold more active than paclitaxel against… Expand
Review
2002
Review
2002
P‐glycoprotein (P‐GP)‐based multidrug resistance (MDR) and undesirable side effects are significant drawbacks to the clinical use… Expand
2001
2001
PURPOSE Protein kinase A type I (PKAI) and the epidermal growth factor receptor (EGFR) play a role in neoplastic transformation… Expand
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2001
2001
By flexibly docking 9593 compounds of the NCI-3D database against the refined structure of beta-tubulin using DOCK 4.0, a long… Expand
Highly Cited
2000
Highly Cited
2000
IDN5109 is a new taxane, derived from 14beta-hydroxy-10-deacetylbaccatin III, selected for its lack of cross-resistance in tumor… Expand
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2000
2000
Abstract Using a model of human cervical cancer (ME-180 cells), the anti-tumour activity of paclitaxel was compared to that of… Expand
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Highly Cited
1999
Highly Cited
1999
Clinically available taxanes represent one of the most promising class of antitumor agents, despite several problems with their… Expand
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1999
1999
An HPLC assay was developed to determine the paclitaxel analogue 13-(N-tert.-butoxycarbonyl-beta-isobutylisoserinyl)-14-hydroxyb… Expand