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orexins

Known as: Orexins [Chemical/Ingredient], Hypocretins, hypocretin 
Neuropeptide hormones that play a role in regulating a variety of behavioral and physiological processes in response to motivational stimuli.
National Institutes of Health

Related topics

Related topics

16 relations
HCRT geneHypothalamic HormonesIn BloodProcess of secretion

Narrower (3)

HCRT protein, humanorexin Aorexin B

Broader (1)

Neuropeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Hypothalamic neuropeptides and the regulation of appetite
Highly Cited
2010
Highly Cited
2010
Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats
RationaleAnatomical studies have shown that the paraventricular nucleus of the thalamus (PVT) innervates areas of the forebrain… 
Highly Cited
2009
Highly Cited
2009
Orexin/hypocretin signaling at the orexin 1 receptor regulates cue‐elicited cocaine‐seeking
The orexin/hypocretin system has recently been implicated in reward‐processing and addiction. We examined the involvement of the… 
Highly Cited
2008
Highly Cited
2008
Rapid eye movement sleep disturbances in Huntington disease.
BACKGROUND Sleep disorders including insomnia, movements during sleep, and daytime sleepiness are common but poorly studied in… 
Highly Cited
2007
Highly Cited
2007
Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect.
Neurons in the lateral hypothalamus (LH) that contain hypocretin/orexin have been established as important promoters of arousal… 
Highly Cited
2006
Highly Cited
2006
Hypocretin/Orexin Selectively Increases Dopamine Efflux within the Prefrontal Cortex: Involvement of the Ventral Tegmental Area
Hypocretins (HCRTs) modulate a variety of behavioral and physiological processes, in part via interactions with multiple… 
Review
2005
Review
2005
Neuropeptides and the control of food intake in fish.
Highly Cited
2004
Highly Cited
2004
Behavioral state instability in orexin knockout mice
Narcolepsy is caused by a lack of orexin (hypocretin), but the physiologic process that underlies the sleepiness of narcolepsy is… 
Review
2002
Review
2002
Emerging views of dopamine in modulating sleep/wake state from an unlikely source: PD.
Monoamines (e.g., serotonin [5-HT], norepinephrine [NE], histamine [HA]), and acetylcholine (ACh) modulate wakefulness and slow… 
Highly Cited
2001
Highly Cited
2001
Melanin concentrating hormone depresses synaptic activity of glutamate and GABA neurons from rat lateral hypothalamus
The neuropeptide melanin concentrating hormone (MCH) is synthesised only by neurons of the lateral hypothalamic (LH) area in the… 
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