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orexins
Known as:
Orexins [Chemical/Ingredient]
, Hypocretins
, hypocretin
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Neuropeptide hormones that play a role in regulating a variety of behavioral and physiological processes in response to motivational stimuli.
National Institutes of Health
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Related topics
Related topics
16 relations
HCRT gene
Hypothalamic Hormones
In Blood
Process of secretion
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Narrower (3)
HCRT protein, human
orexin A
orexin B
Broader (1)
Neuropeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness
T. Sakurai
Nature Reviews Neuroscience
2007
Corpus ID: 8932862
Sleep and wakefulness are regulated to occur at appropriate times that are in accordance with our internal and external…
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Highly Cited
2005
Highly Cited
2005
A role for lateral hypothalamic orexin neurons in reward seeking
G. Harris
,
M. Wimmer
,
G. Aston-Jones
Nature
2005
Corpus ID: 4386257
The lateral hypothalamus is a brain region historically implicated in reward and motivation, but the identity of the…
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Highly Cited
2001
Highly Cited
2001
Differential expression of orexin receptors 1 and 2 in the rat brain
J. Marcus
,
C. Aschkenasi
,
+4 authors
J. Elmquist
The Journal of comparative neurology
2001
Corpus ID: 24692229
Orexins (hypocretins) are neuropeptides synthesized in the central nervous system exclusively by neurons of the lateral…
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Highly Cited
1999
Highly Cited
1999
Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation
R. Chemelli
,
J. Willie
,
+12 authors
M. Yanagisawa
Cell
1999
Corpus ID: 89799178
Highly Cited
1999
Highly Cited
1999
Orexin A activates locus coeruleus cell firing and increases arousal in the rat.
J. Hagan
,
R. Leslie
,
+18 authors
N. Upton
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 21862267
The localization of orexin neuropeptides in the lateral hypothalamus has focused interest on their role in ingestion. The…
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Highly Cited
1999
Highly Cited
1999
Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems.
Y. Date
,
Y. Ueta
,
+6 authors
M. Nakazato
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 36399717
We determined the immunohistochemical distributions of orexin-A and orexin-B, hypothalamic peptides that function in the…
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Highly Cited
1998
Highly Cited
1998
Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior
T. Sakurai
,
A. Amemiya
,
+18 authors
M. Yanagisawa
Cell
1998
Corpus ID: 16294729
Highly Cited
1998
Highly Cited
1998
Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems
C. Peyron
,
Devin K. Tighe
,
+4 authors
T. Kilduff
The Journal of Neuroscience
1998
Corpus ID: 16724939
The novel neuropeptides called hypocretins (orexins) have recently been identified as being localized exclusively in cell bodies…
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Highly Cited
1998
Highly Cited
1998
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
L. de Lecea
,
T. Kilduff
,
+12 authors
J. Sutcliffe
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 8187084
We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share…
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Highly Cited
1998
Highly Cited
1998
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
T. Sakurai
,
A. Amemiya
,
+18 authors
M. Yanagisawa
Cell
1998
Corpus ID: 46271203
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