one-carbon metabolic process

Known as: one carbon metabolic process, one-carbon transfer metabolic process, one-carbon metabolism 
The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. [GOC:hjd, GOC:mah, GOC:pde]
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells.
Previous work has shown that some cancer cells are highly dependent on serine/glycine uptake for proliferation. Although serine… (More)
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Review
2013
Review
2013
Serine, glycine and one-carbon units: cancer metabolism in full circle
One-carbon metabolism involving the folate and methionine cycles integrates nutritional status from amino acids, glucose and… (More)
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Highly Cited
2011
Highly Cited
2011
Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism.
BACKGROUND Causes of autism are unknown. Associations with maternal nutritional factors and their interactions with gene variants… (More)
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Review
2010
Review
2010
Compartmentalization of Mammalian folate-mediated one-carbon metabolism.
The recognition that mitochondria participate in folate-mediated one-carbon metabolism grew out of pioneering work beginning in… (More)
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Highly Cited
2008
Highly Cited
2008
Folate-mediated one-carbon metabolism.
Tetrahydrofolate (THF) polyglutamates are a family of cofactors that carry and chemically activate one-carbon units for… (More)
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Highly Cited
2008
Highly Cited
2008
One-carbon metabolism-related gene polymorphisms and risk of breast cancer.
Environmental exposures and/or genetic background in Japanese population, which might contribute to the relatively low breast… (More)
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Highly Cited
2004
Highly Cited
2004
Uteroplacental insufficiency alters DNA methylation, one-carbon metabolism, and histone acetylation in IUGR rats.
Uteroplacental insufficiency leads to intrauterine growth retardation (IUGR) and increases the risk of insulin resistance and… (More)
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Highly Cited
2004
Highly Cited
2004
Periconceptional dietary intake of choline and betaine and neural tube defects in offspring.
Periconceptional intake of folic acid prevents some neural tube defects (NTDs). Other nutrients may also contribute to NTD… (More)
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Review
1997
Review
1997
Folates and one-carbon metabolism in plants and fungi.
Folate-dependent pathways of one-carbon metabolism are essential for the synthesis of purines, formylmethionyl-tRNA, thymidylate… (More)
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Review
1989
Review
1989
Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism.
The physiological importance of folylpolyglutamates is now well established. These derivatives are the intracellular substrates… (More)
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