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nortilidine

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Segmental hair analysis has been used for monitoring changes of consumption habit of drugs. Contamination from the environment or… Expand
2012
2012
Tilidine exhibits the highest consumption of opioids in Germany. The prodrug is hepatically metabolised in a sequential N… Expand
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2012
2012
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The analgesic activity of tilidine is mediated by its active metabolite, nortilidine… Expand
2008
2008
Tilidine is one of the most widely used narcotics in Germany and Belgium. The compound’s active metabolite nortilidine easily… Expand
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Highly Cited
2006
Highly Cited
2006
A fully validated liquid chromatographic procedure coupled with electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS… Expand
2005
2005
Tilidine, alone or combined with naloxone to prevent drug abuse, is used as an oral opioid analgesic. Although the analgesic… Expand
2002
2002
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy… Expand
Review
1999
Review
1999
The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in… Expand
1999
1999
ZusammenfassungHintergrund: Bei Patienten mit Leber- oder Niereninsuffizienz kann die Therapie mit Opioidanalgetika durch Ver… Expand
Highly Cited
1986
Highly Cited
1986
The effect of intrathecal (i.t.) injection of the analgesic agents, codeine, buprenorphine, tilidine and one of its metabolites… Expand