nortilidine
National Institutes of Health
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Hair testing procedures allow a cumulative reflection of long-term drug abuse and are useful as a test for compliance in clinical…
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy…
Summary Valoron® N is a compound which consists of the prodrug tilidine (CAS 20380-58-9), from which the active metabolite…
ZusammenfassungHintergrund: Bei Patienten mit Leber- oder Niereninsuffizienz kann die Therapie mit Opioidanalgetika durch Ver…
In patients with renal or hepatic failure, the pharmacokinetics of opioids may be affected in several ways, leading to the…
Tilidine is a prodrug from which the active metabolite nortilidine is formed by demethylation. The pharmacokinetics of tilidine…
A fatal intoxication due to the ingestion of tilidine, a narcotic analgesic, in conjunction with ethanol, is described. Tilidine…
A sensitive and specific GLC method is described to determine therapeutic levels of tilidine and its two main metabolites…
SummaryThe analgesic effect of tilidine in rats is completely antagonized by the narcotic antagonist naloxone. Radioreceptor…