nortilidine

 

Topic mentions per year

Topic mentions per year

1976-2017
012319762017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The therapeutic activity of tilidine, an opioid analgesic, is mainly related to its active metabolite nortilidine. Nortilidine… (More)
Is this relevant?
2012
2012
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The analgesic activity of tilidine is mediated by its active metabolite, nortilidine… (More)
Is this relevant?
2012
2012
Tilidine exhibits the highest consumption of opioids in Germany. The prodrug is hepatically metabolised in a sequential N… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
2011
2011
The opioid tilidine is a prodrug which is hepatically metabolized to active nortilidine and bisnortilidine. Due to the increasing… (More)
Is this relevant?
2008
2008
Tilidine is one of the most widely used narcotics in Germany and Belgium. The compound’s active metabolite nortilidine easily… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2007
2007
The objective of the present study was to evaluate the pharmacokinetics of tilidine (CAS 20380-58-9), naloxone (CAS 465-65-6) and… (More)
Is this relevant?
2006
2006
A fully validated liquid chromatographic procedure coupled with electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS… (More)
Is this relevant?
2005
2005
Tilidine, alone or combined with naloxone to prevent drug abuse, is used as an oral opioid analgesic. Although the analgesic… (More)
Is this relevant?
2002
2002
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy… (More)
Is this relevant?
1986
1986
The effect of intrathecal (i.t.) injection of the analgesic agents, codeine, buprenorphine, tilidine and one of its metabolites… (More)
Is this relevant?