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Validation of new methods.
Important considerations in analytical method validation will be discussed and may be used as guidance by scientists wishing to develop and validate analytical methods. Expand
Review of Biologic Matrices (Urine, Blood, Hair) as Indicators of Recent or Ongoing Cannabis Use
The cannabis influence factor was demonstrated as a better tool to interpret the concentrations of THC and its metabolites in blood in forensic cases and therefore it was proposed to assume absolute driving inability because of cannabis intoxication from a CIF ≥10. Expand
Chromatographic methods for the determination of markers of chronic and acute alcohol consumption.
  • F. Musshoff
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical…
  • 5 December 2002
The development in chromatographic methods for the determination of markers of alcohol consumption, including ethanol in body fluids, ethanol congeners, fatty acid ethyl esters, ethyl glucuronide, cocaethylene, phosphatidylethanol, 5-hydroxytryptophol, dolichol, ketone bodies, acetaldehyde-protein adducts, and salsolinol are summarized. Expand
Concentrations of Tramadol and O‐desmethyltramadol Enantiomers in Different CYP2D6 Genotypes
YP2D6 genotype determined concentrations of O‐desmethyltramadol enantiomers and influenced efficacy of tramadol treatment and in PMs, non‐response rates to tramadols treatment increased fourfold compared with the other genotypes. Expand
Driving under the influence of synthetic cannabinoids (“Spice”): a case series
Police as well as forensic toxicologists and other groups should become familiar with the effects of synthetic cannabinoid use, and be aware of the fact that drug users may shift to these “legal” alternatives due to their nondetectability by commonly used drug screening tests based on antibodies. Expand
Ricin poisoning and forensic toxicology.
The origin, biochemistry, toxicity, and analytical procedures for the determination of ricin are summarized and the homicide of Markov is described as well as recent cases of criminal ricin use. Expand
Two fatalities associated with synthetic opioids: AH-7921 and MT-45.
In this study, two fatalities associated with the synthetic opioids AH-7921 and MT-45 are reported and deaths of the young individuals could be, by exclusion of other causes of death, attributed to the consumption of an overdose of AH- 7921 andMT-45. Expand
Analytical pitfalls in hair testing
This review focuses on possible pitfalls in hair testing procedures, and modern analytical procedures for the determination of drugs in hair specimens—mainly by gas chromatography–mass spectrometry (GC–MS) and liquid chromatography-mass spectromaetry (LC–MS)—are reviewed and critically discussed. Expand
Determination of biological markers for alcohol abuse.
  • F. Musshoff, T. Daldrup
  • Chemistry, Medicine
  • Journal of chromatography. B, Biomedical sciences…
  • 21 August 1998
No laboratory test exists that is reliable enough for the exact diagnosis of alcoholism, so the combination of physician interview, questionnaire and laboratory markers is necessary for the diagnosis. Expand
Knock-out drugs: their prevalence, modes of action, and means of detection.
A careful medical history and physical examination and the careful taking of biological samples for toxicological analysis form the basis for the detection of drug-facilitated crimes. Expand