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Tilidine

Known as: 3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, trans-(+-)-, Tilidate, Tilidine [Chemical/Ingredient] 
An opioid analgesic used similarly to MORPHINE in the control of moderate to severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1097)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… Expand
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2015
2015
Segmental hair analysis has been used for monitoring changes of consumption habit of drugs. Contamination from the environment or… Expand
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Highly Cited
2007
Highly Cited
2007
ObjectiveDuring the past few years there have been changes in the availability of opioids in Spain, and new policies on… Expand
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2006
2006
A fully validated liquid chromatographic procedure coupled with electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS… Expand
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Review
2005
Review
2005
  • Jörn Lötsch
  • Journal of pain and symptom management
  • 2005
  • Corpus ID: 46171778
The metabolism of opioids closely relates to their chemical structure. Opioids are subject to O-dealkylation, N-dealkylation… Expand
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Review
2004
Review
2004
Persistent non-malignant pain is common, often neglected and under-treated among older persons. Some older adults do not complain… Expand
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2002
2002
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy… Expand
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Review
1999
Review
1999
The liver is the major site of biotransformation for most opioids. Thus, the disposition of these drugs may be affected in… Expand
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1986
1986
The effect of intrathecal (i.t.) injection of the analgesic agents, codeine, buprenorphine, tilidine and one of its metabolites… Expand
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1983
1983
Abstract The effects of the opioid tilidine and the opiate antgonist naloxone on somatosensory evoked potentials (SSEP) and pain… Expand
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