Tilidine

Known as: 3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, trans-(+-)-, Tilidate, Tilidine [Chemical/Ingredient] 
An opioid analgesic used similarly to MORPHINE in the control of moderate to severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1097)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2016
0519722016

Papers overview

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2007
2007
The objective of the present study was to evaluate the pharmacokinetics of tilidine (CAS 20380-58-9), naloxone (CAS 465-65-6) and… (More)
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2005
2005
Tilidine, alone or combined with naloxone to prevent drug abuse, is used as an oral opioid analgesic. Although the analgesic… (More)
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2002
2002
The disposition of nortildine, the active metabolite of the synthetic opioid drug tilidine, was investigated in healthy… (More)
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2001
2001
The aim of the present study was to investigate the pharmacokinetics of tilidine and its metabolites during the dialysis… (More)
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2000
2000
As has been demonstrated in binding studies the two opioids tilidine (CAS 27107-79-7)/naloxone (CAS 357-08-4) and tramadol (CAS… (More)
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1986
1986
The effect of intrathecal (i.t.) injection of the analgesic agents, codeine, buprenorphine, tilidine and one of its metabolites… (More)
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1986
1986
Tilidine is an opioid analgesic that has been abused predominantly by the oral route. Studies of parenterally administered… (More)
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1983
1983
The effects of the opioid tilidine and the opiate antagonist naloxone on somatosensory evoked potentials (SSEP) and pain ratings… (More)
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1978
1978
The analgesic effect of tilidine in rats is completely antagonized by the narcotic antagonist naloxone. Radioreceptor assays… (More)
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1976
1976
A fatal poisoning case due to the combination of a relative overdose of barbiturates (600 mg daily) and 750 mg of tilidine is… (More)
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