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Nogalamycin is an anthracycline antibiotic that has been shown to exhibit significant cytotoxicity. Its biological activity… Expand Nogalamycin is an anthracycline polyketide antibiotic that contains two deoxysugars, at positions C-1 and C-7. Previous… Expand The effect of DNA binding on poisoning of human DNA TOP1 has been studied using a pair of related anthracyclines which differ… Expand Defects in DNA, e.g., unpaired/bulged nucleotides, are repaired by specific repair enzymes. Understanding the dynamics and… Expand The interaction of the anthracycline antibiotic nogalamycin with the single 5'-CpG binding site at the centre of the hexamer… Expand The anthracycline antibiotic nogalamycin differs from the more common daunomycin-type anthracyclines by substitution on both ends… Expand The three-dimensional molecular structures of the complexes between a novel antitumor drug nogalamycin and its derivative U-58872… Expand The nogalamycin-d(A-G-C-A-T-G-C-T) complex (two drugs per duplex) has been generated in aqueous solution and its structure… Expand The interactions between a novel antitumor drug nogalamycin with the self-complementary DNA hexamer d(CGTACG) have been studied… Expand