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nitroaspirin

Known as: Benzoic Acid, 2-(Acetyl-oxy)-3-[(nitrooxy)methyl]phenyl Ester, Nitric Oxide-Releasing Aspirin Derivative, nitric oxide-releasing aspirin 
A nitric oxide (NO) donating derivative of acetylsalicylic acid with anti-inflammatory, analgesic, antipyretic, antithrombotic, gastroprotective and… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (5)

Anti-Inflammatory Agents, Non-SteroidalAspirinCysteine Proteinase InhibitorsFibrinolytic Agents

Narrower (1)

NCX 4016
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Fatty aspirin: a new perspective in the prevention of dementia of Alzheimer's type?
Alzheimer's disease (AD) leads to a dramatic decline in cognitive abilities and memory. A more modest disruption of memory often… 
2007
2007
Functional effects of nitric oxide-releasing aspirin on vein conduits of diabetic patients undergoing CABG.
2007
2007
Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.
We recently reported that NCX-4016, a derivative of aspirin containing a nitro moiety that releases nitric oxide (NO) in a… 
2006
2006
The Effect of NCX4016 [2-Acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl Ester] on the Consequences of Ischemia and Reperfusion in the Streptozotocin Diabetic Rat
The aim of this study was to assess the effect of chronic administration of NCX4016 [2 acetoxy-benzoate 2-(2-nitroxymethyl… 
2005
2005
Ultrastructural investigations on protective effects of NCX 4016 (nitroaspirin) on macrovascular endothelium in diabetic Wistar rats.
The effect of a nitric oxide-donating aspirin derivative, 2-acetoxy-benzoate 3-(nitroxy-methyl)phenyl ester (NCX 4016), and… 
2003
2003
Implications of reactive oxygen species and cytokines in gastroprotection against stress-induced gastric damage by nitric oxide releasing aspirin
Abstract Background and aims. Nitric oxide-releasing aspirin (NO-ASA) has been shown to inhibit cyclo-oxygenase and prostaglandin… 
2003
2003
Effect of nitric oxide-donating agents on human monocyte cyclooxygenase-2.
2003
2003
Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats.
Review
2002
Review
2002
Nitric oxide-releasing drugs: a novel class of effective and safe therapeutic agents.
Nitric oxide (NO) deficiency has been implicated in many pathologic processes, thus providing a solid biological basis for the… 
Highly Cited
2001
Highly Cited
2001
Vasorelaxant effects of a nitric oxide‐releasing aspirin derivative in normotensive and hypertensive rats
Nonsteroidal anti‐inflammatory drugs have been reported to exacerbate hypertension and to interfere with the effectiveness of… 
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