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NCX 4016

Known as: NCX-4016 
National Institutes of Health

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Broader (1)

nitroaspirin

Papers overview

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2007
2007
Prevention of transient endothelial dysfunction in acute exercise: A friendly fire?
2007
2007
Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.
We recently reported that NCX-4016, a derivative of aspirin containing a nitro moiety that releases nitric oxide (NO) in a… 
2007
2007
Cytochrome P450 is responsible for nitric oxide generation from NO-aspirin and other organic nitrates.
Nitric oxide (NO) biotransformation from NO-aspirin (NCX-4016) is not clearly understood. We have previously reported that… 
2006
2006
Nitric oxide and cisplatin resistance: NO easy answers.
Cisplatin is one of the most widely used chemotherapeutic drugs for treating cancer. Initially, platinum-based therapies are very… 
2004
2004
Cooperation between Aspirin-Triggered Lipoxin and Nitric Oxide (NO) Mediates Antiadhesive Properties of 2-(Acetyloxy)benzoic Acid 3-(Nitrooxymethyl)phenyl Ester (NCX-4016) (NO-Aspirin) on Neutrophil…
2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) is a nitric oxide (NO)-releasing derivative of aspirin that… 
2003
2003
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
Highly Cited
2001
Highly Cited
2001
Vasorelaxant effects of a nitric oxide‐releasing aspirin derivative in normotensive and hypertensive rats
Nonsteroidal anti‐inflammatory drugs have been reported to exacerbate hypertension and to interfere with the effectiveness of… 
2000
2000
A common pathway for nitric oxide release from NO-aspirin and glyceryl trinitrate.
NO-Aspirin (NCX-4016) releases nitric oxide (NO) in biological systems through as yet unidentified mechanisms. In LLC-PK1 kidney… 
1999
1999
Nitric oxide-releasing NSAIDs: GI-safe antithrombotics.
Aspirin is increasingly being used for long-term prophylaxis of myocardial infarction and stroke, but its use is limited by… 
1998
1998
Cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal anti-inflammatory drugs and gastric mucosal responses.
Occurrence of gastrointestinal damage and delayed healing of pre-existing ulcer are commonly observed in association with… 
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