nicotine metabolism

Known as: metabolism nicotine, nicotine metabolic process 
The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine. [GOC:sm, ISBN:0198547684]
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Understanding the basic and clinical pharmacology of nicotine provides a basis for improved prevention and treatment of tobacco… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Several studies have reported that female smokers have a higher risk of lung cancer than male smokers. This could be… (More)
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Highly Cited
2004
Highly Cited
2004
Smoking mentholated cigarettes has been suggested to convey a greater cancer risk compared with smoking nonmentholated cigarettes… (More)
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Highly Cited
2004
Highly Cited
2004
Genetically variable CYP2A6 is the primary enzyme that inactivates nicotine to cotinine. Our objective was to investigate allele… (More)
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Highly Cited
2002
Highly Cited
2002
Cigarette smoking is the foremost modifiable risk factor for adverse pregnancy outcomes. Nicotine is a suspected fetal… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Lung cancer rates are lower in Asians and Latinos than in whites. Ethnic differences in nicotine metabolism might… (More)
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Highly Cited
1998
Highly Cited
1998
Nicotine is the primary compound in tobacco that establishes and maintains tobacco dependence. Most of this nicotine is… (More)
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Highly Cited
1998
Highly Cited
1998
CONTEXT Racial differences in tobacco-related diseases are not fully explained by cigarette-smoking behavior. Despite smoking… (More)
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Highly Cited
1997
Highly Cited
1997
Nicotine is primarily metabolized to cotinine by cytochromes P450 (CYPs). The degree of variation in the metabolism of nicotine… (More)
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Highly Cited
1994
Highly Cited
1994
The objectives of this study were to 1) quantitatively assess human exposure to various metabolites of nicotine, 2) examine the… (More)
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