nicotinamide-beta-riboside

Known as: nicotinamide ribonucleoside, nicotinamide ribose, nicotinamide riboside 
 
National Institutes of Health

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Broader (1)

Niacinamide
analogs & derivatives

Papers overview

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Review
2016
Review
2016
From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.
Cellular senescence is a complex stress response that permanently arrests the proliferation of cells at risk for oncogenic… (More)
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Highly Cited
2016
Highly Cited
2016
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to senescence during aging. We… (More)
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Highly Cited
2014
Highly Cited
2014
Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to… (More)
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Highly Cited
2014
Highly Cited
2014
Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss.
Intense noise exposure causes hearing loss by inducing degeneration of spiral ganglia neurites that innervate cochlear hair cells… (More)
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Highly Cited
2013
Highly Cited
2013
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer…
Nicotinamide adenine dinucleotide (NAD)(+), a coenzyme involved in redox activities in the mitochondrial electron transport chain… (More)
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Highly Cited
2012
Highly Cited
2012
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
As NAD(+) is a rate-limiting cosubstrate for the sirtuin enzymes, its modulation is emerging as a valuable tool to regulate… (More)
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Review
2007
Review
2007
NAD+ metabolism in health and disease.
Nicotinamide adenine dinucleotide (NAD(+)) is both a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming… (More)
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Highly Cited
2006
Highly Cited
2006
Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.
Axonal degeneration occurs in many neurodegenerative diseases and after traumatic injury and is a self-destructive program… (More)
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Highly Cited
2004
Highly Cited
2004
Discoveries of Nicotinamide Riboside as a Nutrient and Conserved NRK Genes Establish a Preiss-Handler Independent Route to NAD+ in Fungi and Humans
NAD+ is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in… (More)
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Review
2003
Review
2003
Short-chain dehydrogenases/reductases (SDR): the 2002 update.
Short-chain dehydrogenases/reductases (SDR) form a large, functionally heterogeneous protein family presently with about 3000… (More)
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