Niacinamide

Known as: Pellagra-Preventing Factor, b3 vitamin, Niacinamide [Chemical/Ingredient] 
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio… (More)
National Institutes of Health

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1-benzylnicotinamide2-chloronicotinamide4-phenoxynicotinamide6-bromo-7-hydroxycoumarin-4-ylmethylnicotinamide
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AVOBENZONE 3 g in 100 g TOPICAL CREAM [PONDS VAO-B3]Allantoin 0.02 mg in 1 mL TOPICAL CREAM [ZAREE All Kii Coconut Water]B-SCORBIC TABCENTRUM TAB
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
BACKGROUND & AIMS We previously established long-term culture conditions under which single crypts or stem cells derived from… (More)
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Review
2009
Review
2009
Understanding the Warburg effect: the metabolic requirements of cell proliferation.
In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the… (More)
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Highly Cited
2009
Highly Cited
2009
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
AMP-activated protein kinase (AMPK) is a metabolic fuel gauge conserved along the evolutionary scale in eukaryotes that senses… (More)
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Highly Cited
2009
Highly Cited
2009
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1.
Many metabolic and physiological processes display circadian oscillations. We have shown that the core circadian regulator, CLOCK… (More)
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Highly Cited
2004
Highly Cited
2004
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
NF-kappaB is responsible for upregulating gene products that control cell survival. In this study, we demonstrate that SIRT1, a… (More)
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Highly Cited
2002
Highly Cited
2002
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
BACKGROUND Cutaneous hyperpigmentation occurs in multiple conditions. In addition, many Asian women desire a lighter skin colour… (More)
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Highly Cited
2002
Highly Cited
2002
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.
The Saccharomyces cerevisiae Sir2 protein is an NAD(+)-dependent histone deacetylase that plays a critical role in… (More)
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Highly Cited
2001
Highly Cited
2001
Negative control of p53 by Sir2alpha promotes cell survival under stress.
The NAD-dependent histone deacetylation of Sir2 connects cellular metabolism with gene silencing as well as aging in yeast. Here… (More)
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Highly Cited
1991
Highly Cited
1991
Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
A randomised double-blind prevention trial with a factorial design was conducted at 33 centres in seven countries to determine… (More)
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Review
1988
Review
1988
DNA damage and oxygen radical toxicity.
A major portion of the toxicity of hydrogen peroxide in Escherichia coli is attributed to DNA damage mediated by a Fenton… (More)
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