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Niacinamide

Known as: Pellagra-Preventing Factor, b3 vitamin, Niacinamide [Chemical/Ingredient] 
The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (16)

1-benzylnicotinamide2-chloronicotinamide4-phenoxynicotinamide6-bromo-7-hydroxycoumarin-4-ylmethylnicotinamide
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AVOBENZONE 3 g in 100 g TOPICAL CREAM [PONDS VAO-B3]Allantoin 0.02 mg in 1 mL TOPICAL CREAM [ZAREE All Kii Coconut Water]B-SCORBIC TABCENTRUM TAB
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Papers overview

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Review
2019
Review
2019
PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers
Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination… Expand
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Highly Cited
2011
Highly Cited
2011
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
BACKGROUND & AIMS We previously established long-term culture conditions under which single crypts or stem cells derived from… Expand
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Highly Cited
2009
Highly Cited
2009
Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
Circadian Oscillations The 24-hour day-night cycle plays an important role in mammalian physiology and behavior and, as most… Expand
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Highly Cited
2004
Highly Cited
2004
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
NF‐κB is responsible for upregulating gene products that control cell survival. In this study, we demonstrate that SIRT1, a… Expand
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Highly Cited
2002
Highly Cited
2002
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1*
The Saccharomyces cerevisiae Sir2 protein is an NAD+-dependent histone deacetylase that plays a critical role in transcriptional… Expand
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Highly Cited
2001
Highly Cited
2001
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
Abstract The NAD-dependent histone deacetylation of Sir2 connects cellular metabolism with gene silencing as well as aging in… Expand
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Highly Cited
2001
Highly Cited
2001
Negative control of p53 by Sir2alpha promotes cell survival under stress.
The NAD-dependent histone deacetylation of Sir2 connects cellular metabolism with gene silencing as well as aging in yeast. Here… Expand
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Highly Cited
1991
Highly Cited
1991
Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
A randomised double-blind prevention trial with a factorial design was conducted at 33 centres in seven countries to determine… Expand
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Review
1988
Review
1988
DNA damage and oxygen radical toxicity.
A major portion of the toxicity of hydrogen peroxide in Escherichia coli is attributed to DNA damage mediated by a Fenton… Expand
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Highly Cited
1969
Highly Cited
1969
Diabetogenic action of streptozotocin: relationship of dose to metabolic response.
The relationship between the dose of intravenously administered streptozotocin (a N-nitroso derivative of glucosamine) and the… Expand
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