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neamine

Known as: Nebramycin X, 2-Desoxy-4-O-(2,6-diamino-2,6-didesoxy-alpha-D-glucopyranosyl)-D-streptamin, Neamin 
The minor component of the neomycin complex, a broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity… 
National Institutes of Health

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Broader (1)

Framycetin

Papers overview

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Highly Cited
2011
Highly Cited
2011
The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?
Highly Cited
2010
Highly Cited
2010
Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives.
The aminoglycoside antibiotics bind to the 16S bacterial rRNA and disturb the protein synthesis. One to four hydroxyl functions… 
Highly Cited
2010
Highly Cited
2010
Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum…
Cationic amphiphiles containing multiple positively charged amino functions define a structurally diverse class of antibacterials… 
Highly Cited
2007
Highly Cited
2007
Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: thermodynamics and effect on the kissing-loop to duplex conversion
Owing to a striking, and most likely fortuitous, structural and sequence similarity with the bacterial 16 S ribosomal A site, the… 
Highly Cited
2004
Highly Cited
2004
A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication.
The neamine part of the aminoglycoside antibiotic neomycin B was conjugated to a 16 mer peptide nucleic acid (PNA) targeting HIV… 
Highly Cited
1999
Highly Cited
1999
Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer.
Highly Cited
1998
Highly Cited
1998
Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA.
Aminoglycoside antibiotics that bind to ribosomal RNA in the aminoacyl-tRNA site (A-site) cause misreading of the genetic code… 
Highly Cited
1989
Highly Cited
1989
Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: correlation of genetic and physical maps of the chloroplast genome.
Mutants resistant to streptomycin, spectinomycin, neamine/kanamycin and erythromycin define eight genetic loci in a linear… 
Highly Cited
1976
Highly Cited
1976
INHIBITION BY NEOMYCIN OF POLYPHOSPHOINOSITIDE TURNOVER IN SUBCELLULAR FRACTIONS OF GUINEA‐PIG CEREBRAL CORTEX IN VITRO
The addition of 10−5 M to 10−3 M neomycin to incubations of subcellular fractions of guinea‐pig cerebral cortex increased the… 
Highly Cited
1970
Highly Cited
1970
Biogenesis of mitochondria: 12. The effects of aminoglycoside antibiotics on the mitochondrial and cytoplasmic protein-synthesizing systems of Saccharomyces cerevisiae
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