Framycetin

Known as: Framycetin [Chemical/Ingredient], (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol, Neomycin B 
An aminoglycoside antibiotic isolated from Streptomyces lavendulae (decaris), mainly containing neomycin B, with broad-spectrum antibacterial… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
05101519532017

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Highly Cited
2009
Highly Cited
2009
Myotonic dystrophy (DM) is a genetic disorder caused by the expression (as RNA) of expanded CTG or CCTG repeats. The alternative… (More)
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2008
2008
Herein is described the identification of RNA internal loops that bind to derivatives of neomycin B, neamine, tobramycin, and… (More)
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Highly Cited
2005
Highly Cited
2005
The crystal structures of six complexes between aminoglycoside antibiotics (neamine, gentamicin C1A, kanamycin A, ribostamycin… (More)
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2003
2003
2-Deoxystreptamine (2-DOS) aminoglycoside antibiotics bind specifically to the central region of the 16S rRNA A site and… (More)
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2003
2003
Aminoglycosides (including neomycin B and tobramycin) exhibit poor uptake by eukaryotic cell lines. When the amines of these… (More)
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1999
1999
BACKGROUND Aminoglycoside antibiotics can target RNA folds with micromolar affinity and inhibit biological processes ranging from… (More)
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1999
1999
A number of aminoglycosides have been reported to interact and interfere with the function of various RNA molecules. Among these… (More)
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1997
1997
Aminoglycoside antibiotics can bind to many different types of RNA molecules. It was of interest to determine the nature of the… (More)
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Highly Cited
1995
Highly Cited
1995
Parathyroid cells express a cell surface receptor, coupled to the mobilization of intracellular Ca2+, that is activated by… (More)
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Highly Cited
1993
Highly Cited
1993
Replication of RNA viruses, such as the human immunodeficiency virus (HIV), is dependent upon multiple specific interactions… (More)
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