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Myotonic dystrophy (DM) is a genetic disorder caused by the expression (as RNA) of expanded CTG or CCTG repeats. The alternative… Expand The crystal structures of six complexes between aminoglycoside antibiotics (neamine, gentamicin C1A, kanamycin A, ribostamycin… Expand Semisynthetic aminoglycoside derivatives may provide a means to selectively target viral RNA sites, including the HIV-1 Rev… Expand Aminoglycosides (including neomycin B and tobramycin) exhibit poor uptake by eukaryotic cell lines. When the amines of these… Expand One of the most important families of antibiotics are the aminoglycosides, including drugs such as neomycin B, paromomycin… Expand Binding of human immunodeficiency virus type 1 (HIV-1) transactivator (Tat) protein to Tat-responsive RNA (TAR) is essential for… Expand The specificity of neomycin B and related aminoglycoside antibiotics in their interaction with the Rev responsive element (RRE… Expand Aminoglycoside antibiotics can bind to many different types of RNA molecules. It was of interest to determine the nature of the… Expand Parathyroid cells express a cell surface receptor, coupled to the mobilization of intracellular Ca, that is activated by… Expand Replication of RNA viruses, such as the human immunodeficiency virus (HIV), is dependent upon multiple specific interactions… Expand