A proton and carbon 13 nuclear magnetic resonance study of neomycin B and its interactions with phosphatidylinositol 4,5-bisphosphate.

@article{Reid1987APA,
  title={A proton and carbon 13 nuclear magnetic resonance study of neomycin B and its interactions with phosphatidylinositol 4,5-bisphosphate.},
  author={D. Reid and K. Gajjar},
  journal={The Journal of biological chemistry},
  year={1987},
  volume={262 17},
  pages={
          7967-72
        }
}
  • D. Reid, K. Gajjar
  • Published 1987
  • Medicine, Chemistry
  • The Journal of biological chemistry
The entire proton NMR spectrum of the aminoglycoside antibiotic neomycin B has been assigned at physiological pH by a combination of two-dimensional J-resolved and J-correlated and nuclear Overhauser enhancement difference spectroscopy. Unambiguous assignment of all four ring systems is possible without recourse to model or derivative compounds by observing nuclear Overhauser enhancements between as well as within rings. The subsequent assignment of the carbon 13 spectrum is simply achieved… Expand
Binding of neomycin to phosphatidylinositol 4,5-bisphosphate (PIP2).
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