nalmefene

Known as: nalmefene [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND There is a large treatment gap in alcohol dependence, and current treatments are only moderately effective in… (More)
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Highly Cited
2013
Highly Cited
2013
This study evaluated the efficacy of as-needed use of the opioid system modulator nalmefene in reducing alcohol consumption in… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Pathological gambling is a disabling disorder experienced by approximately 1%-2% of adults and for which there are few… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Despite the relative success of opiate antagonist medication within controlled clinical trials for alcoholism… (More)
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2004
2004
The opiate antagonist nalmefene has been shown in 2 single-site studies to reduce alcohol consumption and relapse drinking in… (More)
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2003
2003
Opiate antagonist medications have been shown to improve alcoholism treatment, but few human laboratory-based studies… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Nalmefene is a newer opioid antagonist that is structurally similar to naltrexone but with a number of potential… (More)
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1995
1995
Opioid use often causes troublesome constipation as a side-effect. Selective antagonism of the intestinal actions of opioids… (More)
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Highly Cited
1994
Highly Cited
1994
A dozen studies have been published showing that opiate antagonists suppress alcohol drinking in animals, and two independent… (More)
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1991
1991
The involvement of endogenous opioids in control of human food intake and appetite was investigated in a double-blind placebo… (More)
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