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nabumetone

Known as: Nabumetona, 4-(6-methoxy-2-naphthyl)-2-butanone, Nabumétone 
A naphthylalkanone and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Nabumetone is a… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (4)

BRL 14777RelafenRelifRelifex

Broader (2)

ButanonesCyclooxygenase 2 Inhibitors
Degenerative polyarthritisDrug AllergyInflammationLiver diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Determining the Molecular Pathways Underlying the Protective Effect of Non-Steroidal Anti-Inflammatory Drugs for Alzheimer's Disease: A Bioinformatics Approach
2013
2013
Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro
1. Nabumetone is a clinically used non-steroidal anti-inflammatory drug, its biotransformation includes major active metabolite 6… 
Review
2004
Review
2004
Spontaneous Reports of Hypertension Leading to Hospitalisation in Association with Rofecoxib, Celecoxib, Nabumetone and Oxaprozin
Background and objectiveData on file with the US FDA, and other published studies, suggest that the selective cyclo-oxygenase… 
Review
2002
Review
2002
Dose-effect relationships of nonsteroidal anti-inflammatory drugs: a literature review.
Review
2001
Review
2001
The ever-emerging anti-inflammatories. Have there been any real advances?
  • K. Rainsford
  • Journal of Physiology - Paris
  • 2001
  • Corpus ID: 21440382
2001
2001
Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non‐steroidal anti‐inflammatory drug nabumetone
Use of non‐steroidal anti‐inflammatory drugs (NSAIDs) for chemoprevention of colon cancer has been hindered by their potential… 
1995
1995
Gastroduodenal tolerability of nabumetone versus naproxen in the treatment of rheumatic patients.
OBJECTIVE The objective of this endoscopic, double-blind study was to evaluate the gastric tolerability of nabumetone, a novel… 
1994
1994
Comparative Effects of Nabumetone, Sulindac, and Indomethacin on Urinary Prostaglandin Excretion and Platelet Function in Volunteers
Nonsteroidal antiinflammatory drugs differ with respect to their effects on prostaglandin metabolism in various tissues, a… 
1994
1994
A longterm endoscopic evaluation of patients with arthritis treated with nabumetone vs naproxen.
OBJECTIVE To compare the gastrointestinal safety, ulcerogenic potential, and clinical efficacy over 5 years of nabumetone and… 
1992
1992
Worldwide safety experience with nabumetone.
Nabumetone has undergone human clinical premarketing and postmarketing testing for efficacy and safety for about 10 years. In the… 
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