nabumetone

Known as: Nabumetona, 4-(6-methoxy-2-naphthyl)-2-butanone, Nabumétone 
A naphthylalkanone and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Nabumetone is a… (More)
National Institutes of Health

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Topic mentions per year

1982-2018
0102019822018

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2006
2006
BACKGROUND AND OBJECTIVE The search for NSAIDs with less gastrointestinal toxicity led to the introduction of the selective cyclo… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS It has been variably suggested that nonselective NSAIDs and cyclooxygenase (COX)-2 selective inhibitors… (More)
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2002
2002
Aspirin, nonselective nonsteroidal anti-inflammatory drugs (NSAIDs), and specific cyclooxygenase-2 (COX-2) inhibitors each have… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND In comparing aspirin, nonselective nonsteroidal antiinflammatory agents (NSAIDs), and cyclooxygenase (COX)-2… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT Nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal (GI) toxic effects, such as upper GI tract… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS The pathogenesis of nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal damage remains poorly… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The "topical" effect of non-steroidal anti-inflammatory drugs (NSAIDs) seems to be an important cause of NSAID induced… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND & AIMS Nonsteroidal anti-inflammatory drugs (NSAIDs) have well-characterized inhibitory effects on gastric ulcer… (More)
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Highly Cited
1994
Highly Cited
1994
The aim of our study was to characterize a model of human prostaglandin endoperoxide synthase-2 (PGHS-2) expression allowing the… (More)
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1984
1984
Radiotracer methodology was used to study the metabolic fate of 4-(6-methoxy-2-naphthyl)-butan-2-one (nabumetone) after oral… (More)
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