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moxonidine

Known as: 4-Chloro-5-(2-Imidazolidinyldeneamino)-6-Methoxy-2-Methylpyrimidine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine, moxonidin 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Antihypertensive AgentsImidazoles

Narrower (3)

CyntLY-326869Zint

Papers overview

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2009
2009
Adrenergic mechanisms of the Kölliker-Fuse/A7 area on the control of water and sodium intake
2007
2007
S1P-receptors in PC12 and transfected HEK293 cells: Molecular targets of hypotensive imidazoline I1 receptor ligands
2006
2006
Alpha2-adrenergic activation in the lateral parabrachial nucleus induces NaCl intake under conditions of systemic hyperosmolarity
2005
2005
Phenylpropanolamine Constricts Mouse and Human Blood Vessels by Preferentially Activating α2-Adrenoceptors
Phenylpropanolamine (dl-norephedrine) was one of the most widely used therapeutic agents to act on the sympathetic nervous system… 
2004
2004
Imidazoline Receptors but Not α2-Adrenoceptors Are Regulated in Spontaneously Hypertensive Rat Heart by Chronic Moxonidine Treatment
We have recently identified imidazoline I1-receptors in the heart. In the present study, we tested regulation of cardiac I1… 
2003
2003
The I1-imidazoline receptor in PC12 pheochromocytoma cells reverses NGF-induced ERK activation and induces MKP-2 phosphatase
Review
2000
Review
2000
Pharmacology of Moxonidine, an I1‐Imidazoline Receptor Agonist
&NA; Moxonidine is a second‐generation, centrally acting antihypertensive drug with a distinctive mode of action. Moxonidine… 
Highly Cited
1996
Highly Cited
1996
Endogenous monoamines inhibit glutamate transmission in the spinal trigeminal nucleus of the guinea‐pig.
1. With the use of whole‐cell patch clamp recordings in slices of guinea‐pig substantia gelatinosa (SG), we studied the serotonin… 
1996
1996
[3H]RX821002 (2-methoxyidazoxan) binds to alpha 2-adrenoceptor subtypes and a non-adrenoceptor imidazoline binding site in rat kidney.
1990
1990
Central Presynaptic α2-Autoreceptors are Involved in the Blood Pressure-Lowering Effect of Moxonidine
Summary: The α-adrenoceptor–mediated effects of the newly developed antihypertensive drug moxonidine and of clonidine were… 
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