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monocyte chemoattractant protein-3

Known as: Chemotactic Protein-3, Monocyte, CCL7 Chemokine, Monocyte Chemoattractant Protein 3 
A monocyte chemoattractant protein that has activity towards a broad variety of immune cell types. Chemokine CCL7 has specificity for CCR1 RECEPTORS… Expand
National Institutes of Health

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CCL7 protein, human
CCL7 wt AlleleIn BloodProcess of secretionagonists
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Highly Cited
2003
Highly Cited
2003
Association Between Plasma Levels of Monocyte Chemoattractant Protein-1 and Long-Term Clinical Outcomes in Patients With Acute Coronary Syndromes
Background—Monocyte chemoattractant protein-1 (MCP-1) is a chemokine responsible for the recruitment of monocytes to sites of… Expand
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Highly Cited
2001
Highly Cited
2001
Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine…
The aim of this study was to explore further the hypothesis that early stages of normal human hematopoiesis might be coregulated… Expand
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Highly Cited
2001
Highly Cited
2001
Matrix Metalloproteinase Activity Inactivates the CXC Chemokine Stromal Cell-derived Factor-1*
Chemokines provide directional cues for leukocyte migration and activation that are essential for normal leukocytic trafficking… Expand
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Highly Cited
2000
Highly Cited
2000
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.
Tissue degradation by the matrix metalloproteinase gelatinase A is pivotal to inflammation and metastases. Recognizing the… Expand
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Highly Cited
1999
Highly Cited
1999
MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.
The earliest recognizable atherosclerotic lesions are fatty streaks composed of lipid-laden macrophages (foam cells). Circulating… Expand
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Highly Cited
1999
Highly Cited
1999
Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and…
Atopic (AA) and nonatopic (NAA) asthma are characterized by chronic inflammation and local tissue eosinophilia. Many C-C… Expand
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Highly Cited
1998
Highly Cited
1998
EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation.
Dendritic cells (DC) that are stimulated with inflammatory mediators can maturate and migrate from nonlymphoid tissues to… Expand
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Highly Cited
1997
Highly Cited
1997
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
Monocyte chemoattractant protein-1 (MCP-1) is a potent agonist for mononuclear leukocytes and has been implicated in the… Expand
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Highly Cited
1996
Highly Cited
1996
Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.
The CC chemokine eotaxin, identified in guinea pigs and also recently in mice, may be a key element for the selective recruitment… Expand
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Highly Cited
1996
Highly Cited
1996
Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain.
By 24 h after mechanical trauma to the cerebral cortex, astroglial reaction begins and injury sites are infiltrated by activated… Expand
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