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monocarboxylic acid transport
The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore…
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National Institutes of Health
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Highly Cited
2006
Highly Cited
2006
Increased brain monocarboxylic acid transport and utilization in type 1 diabetes.
G. Mason
,
K. Petersen
,
V. Lebon
,
D. Rothman
,
G. Shulman
Diabetes
2006
Corpus ID: 30066658
We hypothesized that increased capacity for brain utilization of nonglucose substrates (monocarboxylic acids [MCAs]) by…
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2006
2006
Modulation of Monocarboxylic Acid Transporter-1 Kinetic Function by the cAMP Signaling Pathway in Rat Brain Endothelial Cells*
Jeffrey P. Smith
,
L. Drewes
Journal of Biological Chemistry
2006
Corpus ID: 24722529
MCT1 (monocarboxylic acid transporter 1) facilitates bidirectional monocarboxylic acid transport across membranes. MCT1 function…
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2005
2005
Specificity of the Na+-dependent monocarboxylic acid transport pathway in rabbit renal brush border membranes
E. Nord
,
S. Wright
,
I. Kippen
,
E. M. Wright
Journal of Membrane Biology
2005
Corpus ID: 10059541
SummaryThe substrate specificity of a Na+-dependent transport pathway forl-lactate was studied in rabbit renal brush border…
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Highly Cited
2001
Highly Cited
2001
MCT1-Mediated Transport of L-Lactic Acid at the Inner Blood–Retinal Barrier: A Possible Route for Delivery of Monocarboxylic Acid Drugs to the Retina
K. Hosoya
,
T. Kondo
,
M. Tomi
,
H. Takanaga
,
S. Ohtsuki
,
T. Terasaki
Pharmaceutical Research
2001
Corpus ID: 24806698
AbstractPurpose. The aim of this study was to characterize L-lactic acid transport using a conditionally immortalized rat retinal…
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Highly Cited
1998
Highly Cited
1998
Lactate Transport by Cortical Synaptosomes from Adult Rat Brain: Characterization of Kinetics and Inhibitor Specificity
M. McKenna
,
J. Tildon
,
J. Stevenson
,
I. Hopkins
,
Xueli Huang
,
R. Couto
Developmental Neuroscience
1998
Corpus ID: 46784862
Since lactate released by glial cells may be a key substrate for energy in neurons, the kinetics for the uptake of L-[U-14C…
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Highly Cited
1997
Highly Cited
1997
Quantitative evaluation of brain distribution and blood-brain barrier efflux transport of probenecid in rats by microdialysis: possible involvement of the monocarboxylic acid transport system.
Y. Deguchi
,
K. Nozawa
,
S. Yamada
,
Y. Yokoyama
,
R. Kimura
Journal of Pharmacology and Experimental…
1997
Corpus ID: 8742093
This study was performed to evaluate quantitatively the brain distribution and the efflux transport across the blood-brain…
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Highly Cited
1995
Highly Cited
1995
Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids.
I. Tamai
,
H. Takanaga
,
+4 authors
A. Tsuji
Biochemical and Biophysical Research…
1995
Corpus ID: 41007227
A molecular mechanism for the intestinal monocarboxylic acid transport was characterized by using a proton/monocarboxylate…
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1993
1993
Intestinal brush‐border transport of the oral cephalosporin antibiotic, cefdinir, mediated by dipeptide and monocarboxylic acid transport systems in rabbits
A. Tsuji
,
I. Tamai
,
Masaru Nakanishi
,
T. Terasaki
,
S. Hamano
The Journal of pharmacy and pharmacology
1993
Corpus ID: 6835355
Abstract— Intestinal absorption of the orally active cephalosporin, cefdinir, was investigated using brush‐border membrane…
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Highly Cited
1990
Highly Cited
1990
Carrier-mediated uptake of nicotinic acid by rat intestinal brush-border membrane vesicles and relation to monocarboxylic acid transport.
M. T. Simanjuntak
,
I. Tamai
,
T. Terasaki
,
A. Tsuji
Journal of Pharmacobio-Dynamics
1990
Corpus ID: 34126102
The intestinal transport of [14C]nicotinic acid was investigated at 27 degrees C by using brush-border membrane vesicles (BBMV…
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1990
1990
Metabolic fuel and amino acid transport into the brain in experimental hypothyroidism.
A. Mooradian
Acta Endocrinologica
1990
Corpus ID: 25180668
The effect of hypothyroidism in the adult rat on blood-brain barrier and muscle transport of hexoses, neutral amino acids, basic…
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