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mitomycin B

Known as: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-, 8-carbamate 
A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus. Bioreduced mitomycin B generates… 
National Institutes of Health

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Mitomycin
mitomycin A

Papers overview

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1986
1986
A systematic study on the chemical stability of mitomycin A and mitomycin B.
The kinetics and mechanisms of the degradation of mitomycin A and mitomycin B in aqueous solution were investigated by means of… 
1985
1985
Lack of influence of the carbamoyl group on the stereochemistry of the acid-catalyzed opening of the aziridine ring of the mitomycins and of congeners.
The acid-catalyzed opening of the aziridine ring of mitomycins A and C is known to occur predominantly with cis stereochemistry… 
1981
1981
Preparation and biological activities of 10-decarbamoyloxy-9-dehydromitomycin B and its analogs.
A new naturally occurring mitomycin, 10-decarbamoyloxy-9-dehydromitomycin B (1), was prepared by treating mitomycin B with sodium… 
1978
1978
Studies related to antitumor antibiotics. Part XIV. Reactions of mitomycin B with DNA.
The reactions of the antitumor antibiotic mitomycin B with DNA were examined using ethidium fluorescence assays. The following…