methylpurine
National Institutes of Health
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Nucleosome structure and repair ofN-methylpurines were analyzed at nucleotide resolution in the divergent GAL1-10 genes of intact…
Malignant melanoma is well known for its primary unresponsiveness to chemotherapy. The mechanisms conferring this intrinsic…
Individuals with a decreased DNA repair capacity are at increased cancer risk. The aim of our investigation was to detect genetic…
N-Methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, is responsible for the removal of a wide variety of…
A lethal DNA adduct induced by methylating agents, 3-methyladenine (m3A), is removed by both the constitutive (Tag) and inducible…
N-Alkylpurines induced in DNA by simple monofunctional alkylating agents are known to be cytotoxic and possibly indirectly…
A new N-methylpurine riboside (doridosine), probably N1-Methylisoguanosine, was isolated from the digestive glands of a…