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Purines

Known as: Purine, 1H-Purine, Purines [Chemical/Ingredient] 
One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of purines are adenine and guanine. Purines are… 
National Institutes of Health

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1-benzylwye2,6-dichloropurine2,6-dithiopurine2-hydroxy-6-methylpurine
In BloodPurine Antimetabolite [EPC]agonistsantagonists & inhibitors

Papers overview

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1984
1984
Conformational analysis of r(CGCGCG) in aqueous solution: an A-type double helical conformation studied by two-dimensional nuclear Overhauser effect spectroscopy.
The conformation of the hexanucleoside pentaphosphate r( CGCGCG ) in aqueous solution was studied by circular dichroism, 1H- and… 
Highly Cited
1981
Highly Cited
1981
Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats.
Treatment of perinatal rats with N-ethyl-N-nitrosourea (EtNU) leads predominantly to brain tumors. The DNA in tissues of 10-day… 
Highly Cited
1973
Highly Cited
1973
Characterization of a feedback-resistant phosphoribosylpyrophosphate synthetase from cultured, mutagenized hepatoma cells that overproduce purines.
A clone of cells in which the regulation of purine metabolism is genetically altered was selected and isolated from chemically… 
1972
1972
Mutants constitutive for nucleoside-catabolizing enzymes in Escherichia coli K12. Isolation, charactrization and mapping.
Highly Cited
1971
Highly Cited
1971
The regulation of purine utilization in bacteria. II. Adenine phosphoribosyltransferase in isolated membrane preparations and its role in transport of adenine across the membrane.
Abstract The uptake of adenine by membrane vesicles of Escherichia coli is accompanied by its conversion to AMP and is stimulated… 
Highly Cited
1960
Highly Cited
1960
Purine Metabolism in Human and Chicken Blood, in Vitro
Purine nucleotides occur in blood but their precursors and turnover rates have not been investigated systematically. Because… 
Review
1959
Review
1959
A mechanism of resistance to 8-azaguanine. I. Microbiological studies on the metabolism of purines and 8 azapurines.
The problem of drug resistance is recognized by clinicians and experimentalists as one of the major difficulties in the… 
1955
1955
Chemical and enzymatic changes associated with mouse liver necrosis in vitro.
Chemical and enzymatic changes have been studied in mouse liver undergoing necrosis or autolysis in vitro by incubating pieces of… 
Highly Cited
1953
Highly Cited
1953
In vitro incorporation of glycine-2-C14 into purines and proteins.
Summary In vitro experiments with whole-cell preparations of Ehrlich carcinoma, Gardner lymphosarcoma, and mouse liver led to… 
Highly Cited
1951
Highly Cited
1951
The biosynthesis of the purines.
GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring…