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methoxy-morpholinyl-doxorubicin

Known as: MMDOX, methoxymorpholinoDX, 3'-deamino-3'-(2(S)-methoxy-4-morpholinyl)doxorubicin 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Doxorubicin

Narrower (2)

FCE 23762pnu 152243
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Heart Transplant Patients with PAMR1(H+) and PAMR2 Rejection Have the Same Amount of Myocardial Injury by Molecular Microscope.
2019
2019
Clinical and Pathological Insights of Myocardial Molecular Profiling: Time to Revise ISHLT Grading System?
Review
2019
Review
2019
Genetic and Genomic Approaches to Predict Cardiac Allograft Rejection
The goal of this paper is to review the current state of and ongoing developments in the detection and diagnosis of cardiac… 
2018
2018
PROTOCOL Product Data Sheet Inhibitors
  • 2018
  • Corpus ID: 53941442
In Vitro PNU-159682 inhibits a panel of human tumor cell lines with IC70 values in the range of 0.07-0.58 nM, and is 2,360to 790… 
2012
2012
Content of latex of Hevea brasiliensis determined by using the FITkit in the nitrile gloves used by the workers and in gloves used as positive and negative controls
directly resuspended in 500 mL of SDS-PAGE sample buffer and centrifuged at 16,000 g. Supernatants were analyzed in an 18… 
2005
2005
Antitumor Activity of Methoxymorpholinyl Doxorubicin: Potentiation by Cytochrome P450 3A Metabolism
Methoxymorpholinyl doxorubicin (MMDX) is a novel liver cytochrome P450 (P450)-activated anticancer prodrug whose toxicity toward… 
2004
2004
Effects of the methoxymorpholino derivative of doxorubicin and its bioactivated form versus doxorubicin on human leukemia and lymphoma cell lines and normal bone marrow
The methoxymorpholino derivative of doxorubicin (MMDX; FCE 23672) has recently entered clinical trials because of its broad… 
2004
2004
470 Efficacy of nemorubicin (MMDX) administered with iodinated oil via hepatic artery (IHA) to patients with unresectable primary hepatocellular carcinoma (HCC): phase II trial
2000
2000
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Methoxymorpholinyl doxorubicin (MMDX; PNU 152243) is a promising doxorubicin derivative currently undergoing clinical evaluation… 
1996
1996
Overcoming PGP-related multidrug resistance. The cyclosporine derivative SDZ PSC 833 can abolish the resistance to methoxy-morpholynil-doxorubicin.
BACKGROUND The results obtained so far in studies designed to neutralize P glycoprotein (PGP)-related multidrug resistance (MDR… 
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