metalloendopeptidase activity

Known as: metalloendoprotease activity, metalloendoproteinase activity 
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two… Expand
National Institutes of Health

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Metalloproteasesmetalloendopeptidase inhibitor activity

Papers overview

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1994
1994
Release of Ca2+ from intracellular organelles by peptide analogues: evidence against involvement of metalloendoproteases in Ca2+ sequestration by the endoplasmic reticulum.
N-Benzyloxycarbonyl-Gly-Phe-amide (Z-Gly-Phe-NH2), a competitive substrate for metalloendoproteases, mobilizes intracellular Ca2… Expand
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1991
1991
Inhibition of translational initiation by metalloendoprotease antagonists. Evidence for involvement of sequestered Ca2+ stores.
Synthetic oligopeptide inhibitors of metalloendoprotease activity have been shown to block membrane fusion events, to slow… Expand
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1991
1991
Effects of SCH 34826, an orally active inhibitor of atrial natriuretic peptide degradation, in healthy volunteers.
Atrial natriuretic peptide is cleared from plasma by clearance receptors and by enzymatic degradation by way of a neutral… Expand
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Highly Cited
1989
Highly Cited
1989
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta.
The effects of transforming growth factor-beta (TGF-beta) on fibroblast collagenolytic activity were investigated to determine if… Expand
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1989
1989
Effects of metalloendoprotease substrates on the human sperm acrosome reaction.
The substrates carbobenzyloxyserylleucylamide, carbobenzyloxyglycylleucylamide and carbobenzyloxyglycylphenylalanylamide were… Expand
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1988
1988
Evidence suggesting a role for sperm metalloendoprotease activity in penetration of zona-free hamster eggs by human sperm.
It has been reported that metalloendoprotease (MEP) activity is involved in somatic cell membrane fusion events and in the sea… Expand
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1987
1987
Oligopeptide inhibitors of metalloendoprotease activity inhibit catecholamine secretion from bovine adrenal chromaffin cells by modulating intracellular calcium homeostasis.
Synthetic oligopeptide inhibitors of metalloendoprotease activity were found to inhibit catecholamine release from intact bovine… Expand
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1987
1987
Biochemical studies of metalloendoprotease activity in the spermatozoa of three mammalian species.
Ejaculated porcine and human spermatozoa, hamster spermatozoa from the cauda epididymidis, isolated hamster sperm heads and… Expand
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1984
1984
Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts.
We previously reported that the cell fusion that occurs during muscle development, when mononucleated myoblasts fuse to form… Expand
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1983
1983
Rat myoblast fusion requires metalloendoprotease activity
The calcium-dependent fusion of cultured rat myoblasts to multinucleate myotubes appears to require the activity of a neutral… Expand
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