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metalloendopeptidase activity

Known as: metalloendoprotease activity, metalloendoproteinase activity 
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two… 
National Institutes of Health

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Metalloproteasesmetalloendopeptidase inhibitor activity

Papers overview

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1996
1996
A sensitive and rapid fluorescence-based assay for determination of tetanus toxin peptidase activity.
The light chain of tetanus toxin (TeNT-L chain), endowed with a zinc metalloendopeptidase activity, cleaves specifically the… 
1994
1994
Release of Ca2+ from intracellular organelles by peptide analogues: evidence against involvement of metalloendoproteases in Ca2+ sequestration by the endoplasmic reticulum.
N-Benzyloxycarbonyl-Gly-Phe-amide (Z-Gly-Phe-NH2), a competitive substrate for metalloendoproteases, mobilizes intracellular Ca2… 
1991
1991
Application of bimane-peptide substrates to spectrofluorometric assays of metalloendopeptidases.
A spectrofluorometric method for sensitive determination of metalloendopeptidase activity has been developed by using a bimane… 
1988
1988
Evidence suggesting a role for sperm metalloendoprotease activity in penetration of zona-free hamster eggs by human sperm.
It has been reported that metalloendoprotease (MEP) activity is involved in somatic cell membrane fusion events and in the sea… 
1988
1988
Metalloendoprotease inhibitors block protein synthesis, intracellular transport, and endocytosis in hepatoma cells.
Fusion of membrane vesicles has been implicated in many intracellular processes including the transport of proteins destined for… 
1987
1987
Biochemical studies of metalloendoprotease activity in the spermatozoa of three mammalian species.
Ejaculated porcine and human spermatozoa, hamster spermatozoa from the cauda epididymidis, isolated hamster sperm heads and… 
1987
1987
The soluble metalloendoprotease required in myoblast fusion remains intracellular.
Highly Cited
1985
Highly Cited
1985
Requirement for metalloendoprotease in exocytosis: Evidence in mast cells and adrenal chromaffin cells
Highly Cited
1984
Highly Cited
1984
Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts.
We previously reported that the cell fusion that occurs during muscle development, when mononucleated myoblasts fuse to form… 
1984
1984
Mep-1 gene controlling a kidney metalloendopeptidase is linked to the major histocompatibility complex in mice.
Meprin, a glycoprotein with potent metalloendopeptidase activity, is an integral component of the brush border membrane of mouse… 
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