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melatonin biosynthetic process

Known as: melatonin synthesis, melatonin formation, melatonin anabolism 
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). [GOC:mah, ISBN:0198506732]
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
Extraocular light exposure does not suppress plasma melatonin in humans.
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal melatonin synthesis, and/or a… 
Highly Cited
1994
Highly Cited
1994
Ultraviolet regulation of neuroendocrine and circadian physiology in rodents
Highly Cited
1993
Highly Cited
1993
Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid
Highly Cited
1988
Highly Cited
1988
Examination of in vitro melatonin secretion from superfused trout (Salmo gairdneri) pineal organs maintained under diel illumination or continuous darkness.
Highly Cited
1987
Highly Cited
1987
Rhythmic melatonin biosynthesis in a photoreceptive pineal organ: a study in the pike.
Activities of pineal N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase, involved in the biosynthesis of melatonin… 
Highly Cited
1987
Highly Cited
1987
Effect of asymmetrical reductions of photoperiod on pineal melatonin, locomotor activity and gonadal condition of male Syrian hamsters.
This study investigated the relationship of two overt circadian rhythms, locomotor activity and melatonin synthesis in the pineal… 
Highly Cited
1986
Highly Cited
1986
Magnetic field effects on pineal gland melatonin synthesis: comparative studies on albino and pigmented rodents
1985
1985
Ovine pineal alpha 1-adrenoceptors: characterization and evidence for a functional role in the regulation of serum melatonin.
Plasma melatonin in sheep increases to nocturnal levels rapidly (10-20 min) after dark onset. This increase is blocked by iv… 
Highly Cited
1982
Highly Cited
1982
Pineal is required for testicular maintenance in the turkish hamster (mesocricetus brandti).
The effect of pinealectomy on reproductive function was examined in the Turkish hamster, Mesocricetus brandti. Pinealectomy… 
Highly Cited
1968
Highly Cited
1968
Enzymatic Synthesis of Melatonin in Avian Pineal Body: Extraretinal Response to Light
In the chick pineal body, activity of the melatonin-forming enzyme hydroxyindole-O-methyl transferase is greater in the light… 
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