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melatonin biosynthetic process

Known as: melatonin synthesis, melatonin formation, melatonin anabolism 
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). [GOC:mah, ISBN:0198506732]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Melatonin synthesis in retina: circadian regulation of arylalkylamine N-acetyltransferase activity in cultured photoreceptor cells of embryonic chicken retina
Highly Cited
2002
Highly Cited
2002
In Vivo Disruption of Xenopus CLOCK in the Retinal Photoreceptor Cells Abolishes Circadian Melatonin Rhythmicity without Affecting Its Production Levels
Xenopuslaevis retinas, like retinas from all vertebrate classes, have endogenous circadian clocks that control many aspects of… 
2000
2000
Environmental influences on melatonin secretion in Atlantic cod (Gadus morhua L.) and their relevance to commercial culture
This study investigated the effects of photoperiod and temperature on plasma melatonin secretion in Atlantic cod (Gadus morhua L… 
Highly Cited
1998
Highly Cited
1998
Evidence for melatonin synthesis in rodent Harderian gland: A dynamic in vitro study
ABSTRACT: Melatonin content and release from Harderian glands (HGs) has been measured by an in vitro perifusion technique in… 
1996
1996
Disrupted melatonin-secretion during alcohol withdrawal
Highly Cited
1993
Highly Cited
1993
Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid
1988
1988
An antiserum against chicken hydroxyindole-O-methyltransferase reacts with the enzyme from pineal gland and retina and labels pineal modified photoreceptors.
1985
1985
Ovine pineal alpha 1-adrenoceptors: characterization and evidence for a functional role in the regulation of serum melatonin.
Plasma melatonin in sheep increases to nocturnal levels rapidly (10-20 min) after dark onset. This increase is blocked by iv… 
Highly Cited
1985
Highly Cited
1985
Stress-induced synthesis of melatonin: possible involvement of the endogenous monoamine oxidase inhibitor (tribulin).
1985
1985
Electrical stimulation of the hypothalamic paraventricular nuclei inhibits pineal melatonin synthesis in male rats.
Recent findings have shown that lesions of the hypothalamic paraventricular nuclei (PVN) disrupt the synthesis of melatonin in… 
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