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melatonin biosynthetic process
Known as:
melatonin synthesis
, melatonin formation
, melatonin anabolism
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The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). [GOC:mah, ISBN:0198506732]
National Institutes of Health
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Highly Cited
1998
Highly Cited
1998
Extraocular light exposure does not suppress plasma melatonin in humans.
S. Lockley
,
D. Skene
,
+7 authors
J. Arendt
Journal of Clinical Endocrinology and Metabolism
1998
Corpus ID: 12479741
Light affects the circadian axis in at least two ways. It can cause the acute suppression of pineal melatonin synthesis, and/or a…
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Highly Cited
1994
Highly Cited
1994
Ultraviolet regulation of neuroendocrine and circadian physiology in rodents
G. Brainard
,
Felix M. Barker
,
+4 authors
M. Rollag
Vision Research
1994
Corpus ID: 2544204
Highly Cited
1993
Highly Cited
1993
Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid
K. B. Thomas
,
M. Tigges
,
P. Iuvone
Brain Research
1993
Corpus ID: 29120620
Highly Cited
1988
Highly Cited
1988
Examination of in vitro melatonin secretion from superfused trout (Salmo gairdneri) pineal organs maintained under diel illumination or continuous darkness.
W. Gern
,
S. S. Greenhouse
General and Comparative Endocrinology
1988
Corpus ID: 28031075
Highly Cited
1987
Highly Cited
1987
Rhythmic melatonin biosynthesis in a photoreceptive pineal organ: a study in the pike.
J. Falcón
,
J. Guerlotté
,
P. Voisin
,
J. Collin
Neuroendocrinology
1987
Corpus ID: 23067966
Activities of pineal N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase, involved in the biosynthesis of melatonin…
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Highly Cited
1987
Highly Cited
1987
Effect of asymmetrical reductions of photoperiod on pineal melatonin, locomotor activity and gonadal condition of male Syrian hamsters.
Michael H. Hastings
,
A. P. Walker
,
Joe Herbert
Journal of Endocrinology
1987
Corpus ID: 11567041
This study investigated the relationship of two overt circadian rhythms, locomotor activity and melatonin synthesis in the pineal…
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Highly Cited
1986
Highly Cited
1986
Magnetic field effects on pineal gland melatonin synthesis: comparative studies on albino and pigmented rodents
J. Olcese
,
S. Reuss
Brain Research
1986
Corpus ID: 24270548
1985
1985
Ovine pineal alpha 1-adrenoceptors: characterization and evidence for a functional role in the regulation of serum melatonin.
D. Sugden
,
M. Namboodiri
,
D. Klein
,
J. Pierce
,
R. Grady
,
I. Mefford
Endocrinology
1985
Corpus ID: 30020605
Plasma melatonin in sheep increases to nocturnal levels rapidly (10-20 min) after dark onset. This increase is blocked by iv…
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Highly Cited
1982
Highly Cited
1982
Pineal is required for testicular maintenance in the turkish hamster (mesocricetus brandti).
D. Carter
,
V. Hall
,
L. Tamarkin
,
B. Goldman
Endocrinology
1982
Corpus ID: 23678401
The effect of pinealectomy on reproductive function was examined in the Turkish hamster, Mesocricetus brandti. Pinealectomy…
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Highly Cited
1968
Highly Cited
1968
Enzymatic Synthesis of Melatonin in Avian Pineal Body: Extraretinal Response to Light
J. Lauber
,
J. Boyd
,
J. Axelrod
Science
1968
Corpus ID: 37221904
In the chick pineal body, activity of the melatonin-forming enzyme hydroxyindole-O-methyl transferase is greater in the light…
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