mecasermin

Known as: Recombinant Insulin-Like Growth Factor 1, IGF1, IGF-1 
Recombinant form of endogenous Insulin-like Growth Factor 1 exhibiting mitogenic activity. Clinical Use: Diabetes Mellitus and Amyotrophic Lateral… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
05010019562016

Papers overview

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Review
2017
Review
2017
It has been generally accepted that integrin cell adhesion receptors are involved in growth factor signaling (integrin-growth… (More)
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Highly Cited
2008
Highly Cited
2008
Reduced function mutations in the insulin/IGF-I signaling pathway increase maximal lifespan and health span in many species… (More)
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Highly Cited
2003
Highly Cited
2003
Amyotrophic lateral sclerosis (ALS) is a progressive, lethal neuromuscular disease that is associated with the degeneration of… (More)
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Highly Cited
2003
Highly Cited
2003
We have demonstrated previously that adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic… (More)
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Highly Cited
2003
Highly Cited
2003
Muscle satellite cells are mononuclear cells that remain in a quiescent state until activated when they proliferate and fuse with… (More)
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Highly Cited
2000
Highly Cited
2000
The function of Akt (protein kinase B) is regulated by phosphorylation on two sites conserved within the AGC kinase family: the… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Patients with acute renal failure (ARF) have high morbidity and mortality rates, particularly if they have serious… (More)
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Highly Cited
1998
Highly Cited
1998
Sexually dimorphic growth hormone (GH) secretory pattern is important in the determination of gender-specific patterns of growth… (More)
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Highly Cited
1996
Highly Cited
1996
To ascertain if IGF-1 is a regulator of local muscle growth, total RNA was extracted from rabbit muscle induced to undergo rapid… (More)
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Highly Cited
1988
Highly Cited
1988
Recombinant human insulin-like growth factor I (rhIGF-I) was infused subcutaneously into hypophysectomized rats for as long as 18… (More)
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