malformin C
National Institutes of Health
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Malformin C, a fungal cyclic pentapeptide, has been claimed to have anti-cancer potential, but no in vivo study was available to…
Malformin A₁, a cyclopentapeptide of fungal origin, enhances cellular fibrinolytic activity depending on the existence of a…
We accomplished the solid-phase total synthesis of malformin C, which is adaptable for the easy preparation of various…
Total synthesis of a fungal cyclic peptide, malformin C, recently rediscovered as a G2 checkpoint inhibitor was completed. Our…
A DNA-damaging agent, bleomycin, arrests the cell cycle at the G2 phase of Jurkat cells, which are defective in the G1 checkpoint…
Malformin A is a cyclic pentapeptide with an intramolecular disulfide bridge. The conformation in solution of this molecule has…