Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30.

@article{Zhou2016AspernigrinsWA,
  title={Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30.},
  author={Xuefeng Zhou and W. J. Fang and Suiyi Tan and Xiu-ping Lin and Tianrong Xun and Bingjie Yang and Shuwen Liu and Yonghong Liu},
  journal={Bioorganic & medicinal chemistry letters},
  year={2016},
  volume={26 2},
  pages={361-365}
}
Two new 2-benzylpyridin-4-one containing metabolites, aspernigrins C (3) and D (4), together with six known compounds (1, 2, and 5-8), were isolated from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30. The structures of the new compounds were determined by NMR, MS, and optical rotation analyses. All the isolated compounds were evaluated for their inhibitory activities against infection with HIV-1 SF162 in TZM-bl cells. Malformin C (5) showed the strongest anti-HIV-1 activity with… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

References

Publications referenced by this paper.

Chemical structures of compounds

Y. Kojima, T. Sunazuka, +5 authors S. J. Antibiot. Omura
2009

Similar Papers

Loading similar papers…