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mRNA Precursor

Known as: premRNA, Precursor mRNA, Pre mRNA 
A primary RNA transcript synthesized from a DNA template in eukaryotic nuclei which is post-transcriptionally modified and spliced to produce a… 
National Institutes of Health

Related topics

Related topics

6 relations
Clinical Data Interchange Standards Consortium TerminologyPolypyrimidine Tract-Binding ProteinRNA, MessengerSpliceosomes

Broader (2)

Heterogeneous Nuclear RNARNA Precursors

Papers overview

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Highly Cited
2005
Highly Cited
2005
Spliceosomal introns in the deep-branching eukaryote Trichomonas vaginalis.
Eukaryotes have evolved elaborate splicing mechanisms to remove introns that would otherwise destroy the protein-coding capacity… 
Highly Cited
2004
Highly Cited
2004
Origins of recently gained introns in Caenorhabditis.
The genomes of the nematodes Caenorhabditis elegans and Caenorhabditis briggsae both contain approximately 100,000 introns, of… 
Highly Cited
2001
Highly Cited
2001
Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.
Antisense oligonucleotides (ASOs) that bind target pre-mRNA with high affinity have been shown to alter splicing patterns and… 
Highly Cited
1999
Highly Cited
1999
Serotonin-2C Receptor Pre-mRNA Editing in Rat Brain andin Vitro by Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1*
The interferon-inducible RNA-specific adenosine deaminase (ADAR1) is an RNA editing enzyme implicated in the site-selective… 
Highly Cited
1996
Highly Cited
1996
CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145.
The function of U2 snRNA in splicing is mediated by the proteins of the U2 small nuclear ribonucleoprotein. To identify proteins… 
Highly Cited
1994
Highly Cited
1994
Point mutations in the stem-loop at the 3' end of mouse histone mRNA reduce expression by reducing the efficiency of 3' end formation
Mammalian histone mRNAs end in a highly conserved stem-loop structure, with a six-base stem and a four-base loop. We have… 
Highly Cited
1990
Highly Cited
1990
Control of retroviral RNA splicing through maintenance of suboptimal processing signals
The full-length retroviral transcript serves as genomic RNA for progeny virions, as an mRNA for structural proteins and enzymes… 
Highly Cited
1989
Highly Cited
1989
In vitro reconstitution of functional yeast U2 snRNPs.
A system for the functional reconstitution of yeast U2 snRNPs using synthetic U2 RNAs is described. We use oligonucleotide… 
Highly Cited
1988
Highly Cited
1988
Nuclear pre-mRNA processing in plants: distinct modes of 3'-splice-site selection in plants and animals
The report that human growth hormone pre-mRNA is not processed in transgenic plant tissues (A. Barta, K. Sommergruber, D… 
Highly Cited
1985
Highly Cited
1985
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro
To determine whether a specific nucleotide sequence is required to direct polyadenylation of a simian virus 40 early pre-mRNA in… 
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