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mRNA Precursor
Known as:
premRNA
, Precursor mRNA
, Pre mRNA
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A primary RNA transcript synthesized from a DNA template in eukaryotic nuclei which is post-transcriptionally modified and spliced to produce a…
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National Institutes of Health
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Related topics
Related topics
6 relations
Clinical Data Interchange Standards Consortium Terminology
Polypyrimidine Tract-Binding Protein
RNA, Messenger
Spliceosomes
Broader (2)
Heterogeneous Nuclear RNA
RNA Precursors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Genome-Wide Prediction and Analysis of Yeast RNase III-Dependent snoRNA Processing Signals
Ghada Ghazal
,
Dongling Ge
,
Julien Gervais-Bird
,
Jules Gagnon
,
S. Abou Elela
Molecular and Cellular Biology
2005
Corpus ID: 16894860
ABSTRACT In Saccharomyces cerevisiae, the maturation of both pre-rRNA and pre-small nucleolar RNAs (pre-snoRNAs) involves common…
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Highly Cited
2004
Highly Cited
2004
Origins of recently gained introns in Caenorhabditis.
Avril Coghlan
,
K. H. Wolfe
Proceedings of the National Academy of Sciences…
2004
Corpus ID: 25835869
The genomes of the nematodes Caenorhabditis elegans and Caenorhabditis briggsae both contain approximately 100,000 introns, of…
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Highly Cited
2001
Highly Cited
2001
Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.
J. Karras
,
M. Maier
,
T. Lu
,
A. Watt
,
M. Manoharan
Biochemistry
2001
Corpus ID: 37448477
Antisense oligonucleotides (ASOs) that bind target pre-mRNA with high affinity have been shown to alter splicing patterns and…
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Highly Cited
1999
Highly Cited
1999
Serotonin-2C Receptor Pre-mRNA Editing in Rat Brain andin Vitro by Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1*
Yong Liu
,
R. Emeson
,
C. E. Samuel
Journal of Biological Chemistry
1999
Corpus ID: 866775
The interferon-inducible RNA-specific adenosine deaminase (ADAR1) is an RNA editing enzyme implicated in the site-selective…
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Highly Cited
1998
Highly Cited
1998
Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors.
T. Groß
,
K. Richert
,
C. Mierke
,
M. Lützelberger
,
N. Käufer
Nucleic Acids Research
1998
Corpus ID: 5743286
The SR protein family is involved in constitutive and regulated pre-mRNA splicing and has been found to be evolutionarily…
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Highly Cited
1996
Highly Cited
1996
CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145.
Sandra E. Wells
,
Megan Neville
,
Michelle Haynes
,
Jianhua Wang
,
Hailer Igel
,
Manuel Ares
Genes & Development
1996
Corpus ID: 23296511
The function of U2 snRNA in splicing is mediated by the proteins of the U2 small nuclear ribonucleoprotein. To identify proteins…
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Highly Cited
1996
Highly Cited
1996
Essential nucleotides direct neuron-specific splicing of gamma 2 pre-mRNA.
L. Zhang
,
M. Ashiya
,
T. Sherman
,
P. Grabowski
RNA: A publication of the RNA Society
1996
Corpus ID: 40378382
Tissue-and stage-specific pre-mRNA splicing events are prevalent in mammals, yet molecular details are lacking about these…
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Highly Cited
1990
Highly Cited
1990
Control of retroviral RNA splicing through maintenance of suboptimal processing signals
R. Katz
,
A. Skalka
Molecular and Cellular Biology
1990
Corpus ID: 30692483
The full-length retroviral transcript serves as genomic RNA for progeny virions, as an mRNA for structural proteins and enzymes…
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Highly Cited
1989
Highly Cited
1989
In vitro reconstitution of functional yeast U2 snRNPs.
D. S. McPheeters
,
P. Fabrizio
,
J. Abelson
Genes & Development
1989
Corpus ID: 7083430
A system for the functional reconstitution of yeast U2 snRNPs using synthetic U2 RNAs is described. We use oligonucleotide…
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Highly Cited
1985
Highly Cited
1985
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro
J. Manley
,
H. Yu
,
L. Ryner
Molecular and Cellular Biology
1985
Corpus ID: 21858821
To determine whether a specific nucleotide sequence is required to direct polyadenylation of a simian virus 40 early pre-mRNA in…
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