Spliceosomes

Known as: spliceosome complex location, spliceosomal complex location, spliceosome complex 
Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
0204019882017

Papers overview

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2013
2013
Using the yeast Cryptococcus neoformans, we describe a mechanism by which transposons are initially targeted for RNAi-mediated… (More)
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Highly Cited
2012
Highly Cited
2012
More than 200 proteins copurify with spliceosomes, the compositionally dynamic RNPs catalyzing pre-mRNA splicing. To better… (More)
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2012
2012
A subset of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) patients present pathological… (More)
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2011
2011
More than 200 proteins associate with human spliceosomes, but little is known about their relative abundances in a given… (More)
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2007
2007
The spliceosome is a dynamic macromolecular machine that catalyzes the excision of introns from pre-mRNA. The megadalton-sized… (More)
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2007
2007
Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which genetics is one of the underlying risk factors… (More)
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2000
2000
Most messenger RNA precursors (pre-mRNA) undergo cis-splicing in which introns are excised and the adjoining exons from a single… (More)
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Highly Cited
1998
Highly Cited
1998
Many important cell mechanisms are carried out and regulated by multi-protein complexes, for example, transcription and RNA… (More)
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Highly Cited
1994
Highly Cited
1994
We have isolated and determined the protein composition of the spliceosomal complex C. The pre-mRNA in this complex has undergone… (More)
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1994
1994
Highly purified mammalian spliceosomal complex B contains more than 30 specific protein components. We have carried out UV cross… (More)
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