FAQ

Small Nuclear Ribonucleoproteins

Known as: Small Nuclear RNP, RNP, Small Nuclear, Nuclear Ribonucleoprotein, Small 
Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end… (More)

Topic mentions per year

Topic mentions per year

1979-2017
05101519792017

Related topics

Related topics

16 relations
7SK Small Nuclear RNA, humanIn BloodLSM2 geneProcess of secretion
(More)

Broader (1)

Spliceosomes

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Small Nuclear Ribonucleoproteins
physiological aspects
agonists
RNA Processing
chemical synthesis
Small Nuclear RNA

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle.
In eukaryotic cells, freshly synthesized messenger RNA (pre-mRNA) contains stretches of non-coding RNA that must be excised… (More)
Is this relevant?
2001
2001
Isolation of Small Nuclear Ribonucleoproteins Containing
  • Monique HinterbergerS, Ingvar Petterssong, Joan, Steitz
  • 2001
A fractionation procedure has been developed for the most abundant small nuclear ribonucleoproteins, the Sm snRNPs containing Ul… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.
Activation of the chromosome end-replicating enzyme telomerase can greatly extend the lifespan of normal human cells and is… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex.
We show that addition of SR proteins to in vitro splicing extracts results in a significant increase in assembly of the earliest… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1994
1994
Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly.
Highly purified mammalian spliceosomal complex B contains more than 30 specific protein components. We have carried out UV cross… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 6
  • figure 7
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors.
Exactly how specific splice sites are recognized during the processing of complex precursor messenger RNAs is not clear. Small… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A.
The crystal structure of the RNA binding domain of the U1 small nuclear ribonucleoprotein A, which forms part of the… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles.
  • Denise Spector
  • Proceedings of the National Academy of Sciences…
  • 1990
The structural and functional organization of the cell nucleus has been investigated using three-dimensional reconstruction… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1989
1989
The sphere organelle contains small nuclear ribonucleoproteins.
We show by immunofluorescence microscopy of amphibian oocyte nuclei that small nuclear ribonucleoproteins (snRNPs) occur in… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes.
Electrophoretic separation of ribonucleoprotein particles in a nondenaturing gel was used to analyze the splicing of mRNA… (More)
Is this relevant?