Polypyrimidine Tract-Binding Protein

Known as: Polypyrimidine Tract Binding Protein, PTB Protein, p57 Cytoplasmic RNA Binding Protein 
A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The polypyrimidine tract binding protein (PTB) binds pre-mRNAs to alter splice-site choice. We characterized a series of… (More)
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Highly Cited
2005
Highly Cited
2005
Polypyrimidine tract binding protein (PTB) is known to silence the splicing of many alternative exons. However, exons repressed… (More)
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2005
2005
The polypyrimidine tract binding (PTB) protein is a potent regulator of alternative mRNA splicing. It also participates in other… (More)
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2003
2003
The alpha-actinin gene has a pair of alternatively spliced exons. The smooth muscle (SM) exon is repressed in most cell types by… (More)
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Highly Cited
2000
Highly Cited
2000
Splicing of the c-src N1 exon in neuronal cells depends in part on an intronic cluster of RNA regulatory elements called the… (More)
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Highly Cited
2000
Highly Cited
2000
We studied the role of polypyrimidine tract binding protein in repressing splicing of the c-src neuron-specific N1 exon… (More)
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Highly Cited
1997
Highly Cited
1997
Polypyrimidine tract binding protein (PTB) is a 57 kD hnRNP protein (hnRNP I) that binds to the pyrimidine tract typically found… (More)
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Highly Cited
1997
Highly Cited
1997
The neural cell-specific N1 exon of the c-src pre-mRNA is both negatively regulated in nonneural cells and positively regulated… (More)
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Highly Cited
1995
Highly Cited
1995
Initiation of translation of the human hepatitis C virus (HCV) RNA genome occurs by internal ribosome entry into the 5' noncoding… (More)
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Highly Cited
1991
Highly Cited
1991
The polypyrimidine tract of mammalian introns is recognized by a 62-kD protein (pPTB). Mutations in the polypyrimidine tract that… (More)
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