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loxistatin

Known as: (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester, epoxysuccinyl-leucylamide(3-methyl)butane ethyl ester, ethyl 3-(3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate 
 
National Institutes of Health

Papers overview

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2019
2019
We report an inhibitory covalent labeling and clickable-element-tagging strategy for measuring the absolute activity of a… Expand
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2012
2012
Stefin B (cystatin B) is an endogenous inhibitor of cysteine proteinases localized in the nucleus and the cytosol. Loss-of… Expand
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2006
2006
WF14865Aand B, novel cathepsins B and L inhibitors, were produced and isolated separately from the culture mycelium of a fungal… Expand
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2005
2005
Stefin B (cystatin B) is an inhibitor of lysosomal cysteine cathepsins and does not inhibit cathepsin D, E (aspartic) or… Expand
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1991
1991
1. The absorption, distribution and excretion of loxistatin were studied in normal and dystrophic hamsters. 2. After oral… Expand
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Highly Cited
1991
Highly Cited
1991
Human polymorphonuclear leukocytes (PMNs) converted human big endothelin (bET; 2 microM) to an endothelin-1 (ET-1) like… Expand
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1991
1991
Human polymorphonuclear leukocytes (PMNs, 4 x 10(6)/ml) converted human big endothelin (bET) to an endothelin-1 (ET-1)-like… Expand
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1990
1990
Loxistatin is a possible therapeutic agent of muscular dystrophy. A single oral administration of loxistatin to male rats caused… Expand
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1990
1990
1. The urinary and plasma metabolites of 14C-loxistatin, a new thiol protease inhibitor, were studied after oral administration… Expand
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1989
1989
1. The metabolic fate of loxistatin, ethyl-(+)-(2S,3S)-3-[(S)-3-methyl-1-(3-methyl- butylcarbamoyl)butylcarbamoyl]-2… Expand
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