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loxistatin

Known as: (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester, epoxysuccinyl-leucylamide(3-methyl)butane ethyl ester, ethyl 3-(3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylate 
National Institutes of Health

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aloxistatin

Papers overview

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2019
2019
Inhibitory Covalent Labeling and Clickable-Eu-Tagging-Based ICPMS: Measurement of pH-Dependent Absolute Activities of the Cathepsins in Hepatocyte Lysosomes.
We report an inhibitory covalent labeling and clickable-element-tagging strategy for measuring the absolute activity of a… 
2006
2006
New Cathepsins B and L Inhibitors Produced by Aphanoascus fulvescens I . Taxonomy , Production , Purification and Biological Properties
WF14865Aand B, novel cathepsins B and L inhibitors, were produced and isolated separately from the culture mycelium of a fungal… 
1992
1992
Inhibitory effect of oryzacystatins and a truncation mutant on the replication of poliovirus in infected Vero cells
1991
1991
The disposition of loxistatin and metabolites in normal and dystrophic hamsters.
1. The absorption, distribution and excretion of loxistatin were studied in normal and dystrophic hamsters. 2. After oral… 
1991
1991
Human polymorphonuclear leukocytes generate and degrade endothelin-1 by two distinct neutral proteases.
Human polymorphonuclear leukocytes (PMNs, 4 x 10(6)/ml) converted human big endothelin (bET) to an endothelin-1 (ET-1)-like… 
1990
1990
Metabolic fate of loxistatin in rat.
1. The urinary and plasma metabolites of 14C-loxistatin, a new thiol protease inhibitor, were studied after oral administration… 
1990
1990
An epoxysuccinic acid derivative(loxistatin)-induced hepatic injury in rats and hamsters.
1989
1989
Identification of glutathione conjugate formed from loxistatin in rats.
1. The metabolic fate of loxistatin, ethyl-(+)-(2S,3S)-3-[(S)-3-methyl-1-(3-methyl- butylcarbamoyl)butylcarbamoyl]-2… 
1989
1989
Crystal structure and molecular conformation of E-64, a cysteine protease inhibitor.
In order to elucidate the conformational characteristics of cysteine protease inhibitors contributing to their inhibitory… 
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