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loricrin

Loricrin (312 aa, 26 kDa) is encoded by the human LOR gene. This protein plays a role in the cell envelope structure of terminally differentiated… 
National Institutes of Health

Related topics

Related topics

3 relations
LOR geneStructural gene

Broader (1)

Membrane Proteins

Papers overview

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2016
2016
Proteomic Analysis of Loricrin Knockout Mouse Epidermis.
The crosslinked envelope of the mammalian epidermal corneocyte serves as a scaffold for assembly of the lipid barrier of the… 
2012
2012
Nicotinic acetylcholine receptor stimulation impairs epidermal permeability barrier function and recovery and modulates cornified envelope proteins.
2003
2003
Differential expression of cornified cell envelope precursors in normal skin, intraorally transplanted skin and normal oral mucosa
Summary Background Skin flaps have routinely been used as substitutes for oral mucosa after extensive resection of oral tissues… 
2002
2002
Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system.
The cornified cell envelope, a lipoprotein layer that assembles at the surface of terminally differentiated keratinocytes, is a… 
Highly Cited
2000
Highly Cited
2000
Transgenic Mice Expressing a Mutant Form of Loricrin Reveal the Molecular Basis of the Skin Diseases, Vohwinkel Syndrome and Progressive Symmetric Erythrokeratoderma
Mutations in the cornified cell envelope protein loricrin have been reported recently in some patients with Vohwinkel syndrome… 
Highly Cited
1993
Highly Cited
1993
Analysis of the cornified cell envelope in lamellar ichthyosis.
BACKGROUND Loricrin and involucrin are major precursor proteins to the cornified cell envelope expressed late in epidermal… 
Highly Cited
1993
Highly Cited
1993
Expression of cornifin in squamous differentiating epithelial tissues, including psoriatic and retinoic acid-treated skin.
The expression of cornifin, a putative cross-linked envelope precursor, was investigated in several squamous differentiating… 
Highly Cited
1992
Highly Cited
1992
Expression of loricrin is negatively controlled by retinoic acid in human epidermis reconstructed in vitro.
In epidermis, the last steps of keratinocyte differentiation are characterized by the covalent cross-linking of cornified… 
1992
1992
The Cornified Cell Envelope: Loricrin and Transglutaminases
The cornified cell envelope (CE) of terminally differentiated human epidermis is a complex structure consisting of several… 
1992
1992
Expression of loricrin in skin disorders.
Loricrin, the major component of the cornified envelope, is normally expressed in the granular layer of epidermis during the last… 
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