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LOR gene

Known as: LOR, LORICRIN, Loricrin Gene 
This gene plays a role in the structure of keratinocyte cell envelopes.
National Institutes of Health

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loricrin

Papers overview

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Highly Cited
2009
Highly Cited
2009
Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis.
Highly Cited
2001
Highly Cited
2001
THE EFFECT OF EXPERIENCE ON ADULTS' ACQUISITION OF A SECOND LANGUAGE
Previous research has suggested that child but not adult immigrants to the United States and Canada make regular progress… 
Highly Cited
2001
Highly Cited
2001
Structural Organization and Regulation of the Small Proline-rich Family of Cornified Envelope Precursors Suggest a Role in Adaptive Barrier Function*
The protective barrier provided by stratified squamous epithelia relies on the cornified cell envelope (CE), a structure… 
Highly Cited
1997
Highly Cited
1997
S100A11, S100A10, Annexin I, Desmosomal Proteins, Small Proline-rich Proteins, Plasminogen Activator Inhibitor-2, and Involucrin Are Components of the Cornified Envelope of Cultured Human Epidermal…
The cornified envelope (CE) is an insoluble sheath of ε-(γ-glutamyl)lysine cross-linked protein, which is deposited beneath the… 
Highly Cited
1997
Highly Cited
1997
The molecular pathology of progressive symmetric erythrokeratoderma: a frameshift mutation in the loricrin gene and perturbations in the cornified cell envelope.
The erythrokeratodermas (EKs) are a group of disorders characterized by erythematous plaques associated with variable features… 
Highly Cited
1996
Highly Cited
1996
Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21.
Chromosome 1 reveals in region 1q21 a most remarkable density of genes that fulfill important functions in terminal… 
Highly Cited
1995
Highly Cited
1995
Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein (*)
Loricrin is the major protein of the cornified cell envelope of terminally differentiated epidermal keratinocytes which functions… 
Highly Cited
1994
Highly Cited
1994
Protein composition of cornified cell envelopes of epidermal keratinocytes.
Terminally differentiated mammalian epidermal cells are lined with a 15 nm thick layer of proteins cross-linked by isodipeptide… 
Highly Cited
1991
Highly Cited
1991
Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.
Highly Cited
1991
Highly Cited
1991
Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid.
We have previously shown that loricrin is a major component of the cornified cell envelope (CE) expressed late in epidermal… 
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