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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
TLDR
A large number of the subjects studied had previously been diagnosed with central giant cell granuloma, a type of cancer which can be difficult to treat with conventional chemotherapy. Expand
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
TLDR
A functional classification of cell death subroutines is proposed that applies to both in vitro and in vivo settings and includes extrinsic apoptosis, caspase-dependent or -independent intrinsic programmed cell death, regulated necrosis, autophagic cell death and mitotic catastrophe. Expand
The cornified envelope: a model of cell death in the skin
TLDR
New insights into the molecular mechanisms and the physiological endpoints of cornification are increasing the understanding of the pathological defects of this unique form of programmed cell death, which is associated with barrier malfunctions and ichthyosis. Expand
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
TLDR
An updated classification of cell death subroutines focusing on mechanistic and essential aspects of the process is proposed, and the utility of neologisms that refer to highly specialized instances of these processes are discussed. Expand
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
TLDR
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms. Expand
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
TLDR
The results indicate that c-Abl and p73 are components of a mismatch-repair-dependent apoptosis pathway which contributes to cisplatin-induced cytotoxicity. Expand
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.
TLDR
TAp73 isoforms exert tumor-suppressive functions and indicate an emerging role for Trp73 in the maintenance of genomic stability, as well as hippocampal dysgenesis. Expand
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
TLDR
The Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death. Expand
p73: Friend or foe in tumorigenesis
As p53 and its homologue p73 have significant sequence and functional similarities, p73 might also be expected to act as a tumour suppressor. However, p73 is activated after DNA damage in a way thatExpand
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
TLDR
This study details the 2009 recommendations of the NCCD on the use of cell death-related terminology including ‘entosis’, ‘mitotic catastrophe”,’ ‘necrosis‚ ‘necroptosis‚’ and ‘pyroptotic’. Expand
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