lexitropsin
National Institutes of Health
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Lexitropsins are modular polyamide molecules that are designed to "read" the base sequence of DNA. Lexitropsins constructed of…
Two series of hybrids of a dynemicin A model and DNA minor groove binding lexitropsins were synthesized and their cytotoxic…
We have studied the DNA-binding properties of two thiazole-containing analogues of netropsin which differ by the absence (Thia-Nt…
The syntheses of functional models for bleomycin, which are composed of a simple analog of the metal-complexing moiety of…
Consideration is given to alternative approaches to the development of DNA sequences selective binding agents because of their…
Five groups of lexitropsin oligopeptides have been synthesized that are structurally related to the natural antiviral agents…
The interactions between 20 drugs and a variety of synthetic DNA polymers and natural DNAs were studied by electric linear…
The structural and dynamic aspects of the interaction of the thiazole containing lexitropsin (1) with an oligodeoxyribonucleotide…
MPE‐Fe(EDTA) footprinting of a novel monocationic bis‐furan lexitropsin 6 on a HindIII/EcoRI restriction fragment of pBR322 DNA…
A theoretical study is presented on the complexation to DNA of a monocationic lexitropsin. Energetics and the structures of the…