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lexitropsin

 
National Institutes of Health

Papers overview

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2004
2004
Isopropyl-thiazole ((iPr)Th) represents a new addition to the building blocks of nucleic acid minor groove-binding molecules. The… Expand
2004
2004
Footprinting, capillary electrophoresis, molecular modelling and NMR studies have been used to examine the binding of a short… Expand
Review
2001
Review
2001
DNA is a well characterized intracellular target but its large size and sequential nature make it an elusive target for selective… Expand
Highly Cited
1997
Highly Cited
1997
BACKGROUND Polyamide drugs, such as netropsin, distamycin and their lexitropsin derivatives, can be inserted into a narrow B-DNA… Expand
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1995
1995
An X-ray crystal structure has been solved of the complex of a dicationic lexitropsin with a B-DNA duplex of sequence… Expand
Review
1994
Review
1994
  • J. Lown
  • Journal of molecular recognition : JMR
  • 1994
  • Corpus ID: 10088740
Consideration is given to alternative approaches to the development of DNA sequences selective binding agents because of their… Expand
1992
1992
Five groups of lexitropsin oligopeptides have been synthesized that are structurally related to the natural antiviral agents… Expand
1990
1990
The synthesis and characterization of a series of compounds that contain an N-alkyl-N-nitrosourea functionality linked to DNA… Expand
1988
1988
All 1H-NMR resonances of d-[CATGGCCATG]2 and the 1:1 complex of lexitropsin 1 and the DNA were assigned by the NOE difference… Expand
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1988
1988
Structural and dynamic properties of the self-complementary decadeoxyribonucleotide d(CGCAATTGCG)2 and the interaction between a… Expand