Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Netropsin

Known as: 1H-Pyrrole-2-carboxamide, 4-((((aminoiminomethyl)amino)acetyl)amino)-N-(5-(((3-amino-3-iminopropyl)amino)carbonyl)-1-methyl-1H-pyrrol-3-yl)-1-methyl-, Sinanomycin, Netropsin [Chemical/Ingredient] 
A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
We have constructed derivatives of Streptomyces coelicolor M145 as hosts for the heterologous expression of secondary metabolite… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
H-NS and Lsr2 are nucleoid-associated proteins from Gram-negative bacteria and Mycobacteria, respectively, that play an important… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Full details of the development of a simple, nondestructive, and high-throughput method for establishing DNA binding affinity and… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The sequence and structural selectivity of 15 different DNA binding agents was explored using a novel, thermodynamically rigorous… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
We synthesized a novel anticancer agent MS-247 (2-[[N-[1-methyl-2-[5-[N-[4-[N,N-bis(2-chloroethyl) amino] phenyl]] carbamoyl]-1H… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1990
Highly Cited
1990
We have determined the domains of the mammalian high mobility group (HMG)I chromosomal proteins necessary and sufficient for… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The electropermeabilization (EPN) of living cells allows the uptake of non-permeant molecules and can reveal their potential… Expand
Is this relevant?
Highly Cited
1986
Highly Cited
1986
alpha-Protein is a high mobility group protein originally purified from African green monkey cells based on its affinity for the… Expand
  • figure 1
  • table 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1985
Highly Cited
1985
X-ray analysis of the complex of netropsin with the B-DNA dodecamer of sequence C-G-C-G-A-A-T-T-BrC-G-C-G reveals that the… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
1982
1982
We report a direct technique for determining the binding sites of small molecules on naturally occurring heterogeneous DNA… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?