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leukotriene metabolic process

Known as: leukotriene metabolism 
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
We aimed to measure simultaneously the expression of drug-metabolizing enzymes (DME) and transcription factors (TF) with high… Expand
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Review
2007
Review
2007
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… Expand
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Highly Cited
2007
Highly Cited
2007
Sonic hedgehog (Shh) is a morphogen pivotal for development and tissue maintenance. Biological effects of Shh are mediated… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate various forms of urticaria by a nonallergic mechanism… Expand
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Review
2003
Review
2003
Antileukotrienes are a relatively new class of anti-asthma drugs that either block leukotriene synthesis (5-lipoxygenase… Expand
1999
1999
In spite of intensive research, our understanding of the regulation of expression of 5-LO (the key enzyme in the leukotriene… Expand
Highly Cited
1993
Highly Cited
1993
The variation of the selenium status of leukocytes was used as a tool to investigate the influence of selenium-containing… Expand
Highly Cited
1993
Highly Cited
1993
In humans, dietary n-3 fatty acids ameliorate some chronic inflammatory diseases. In contrast, however, dietary n-3 fatty acids… Expand
Highly Cited
1988
Highly Cited
1988
Little is known about the metabolic fate of the sulfidopeptide leukotrienes (LTC4/D4/E4). Earlier studies using radiolabeled… Expand
Highly Cited
1984
Highly Cited
1984
  • D. Snyder, R. Krell
  • The Journal of pharmacology and experimental…
  • 1984
  • Corpus ID: 24965603
The effect of the leukotriene (LT) antagonist, FPL55712, on the contractile activity of peptide leukotrienes was evaluated in the… Expand