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leukotriene metabolic process

Known as: leukotriene metabolism 
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transcription Factor and Drug-Metabolizing Enzyme Gene Expression in Lymphocytes from Healthy Human Subjects
We aimed to measure simultaneously the expression of drug-metabolizing enzymes (DME) and transcription factors (TF) with high… 
Review
2007
Review
2007
Biosynthesis and metabolism of leukotrienes.
Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO… 
Highly Cited
2007
Highly Cited
2007
Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.
Highly Cited
2003
Highly Cited
2003
Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs.
BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate various forms of urticaria by a nonallergic mechanism… 
Review
2003
Review
2003
Benefit-Risk Assessment of Antileukotrienes in the Management of Asthma
Antileukotrienes are a relatively new class of anti-asthma drugs that either block leukotriene synthesis (5-lipoxygenase… 
Highly Cited
1993
Highly Cited
1993
Selenoenzymes regulate the activity of leukocyte 5-lipoxygenase via the peroxide tone.
Highly Cited
1993
Highly Cited
1993
n-3 fatty acids and cysteinyl-leukotriene formation in humans in vitro, ex vivo, and in vivo.
In humans, dietary n-3 fatty acids ameliorate some chronic inflammatory diseases. In contrast, however, dietary n-3 fatty acids… 
Review
1992
Review
1992
Fish oils in the prevention of atherosclerosis.
Highly Cited
1988
Highly Cited
1988
Metabolism of leukotriene E4 in isolated rat hepatocytes. Identification of beta-oxidation products of sulfidopeptide leukotrienes.
Highly Cited
1984
Highly Cited
1984
Pharmacological evidence for a distinct leukotriene C4 receptor in guinea-pig trachea.
  • D. Snyder, R. Krell
  • The Journal of pharmacology and experimental…
  • 1984
  • Corpus ID: 24965603
The effect of the leukotriene (LT) antagonist, FPL55712, on the contractile activity of peptide leukotrienes was evaluated in the… 
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