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leukotriene metabolic process

Known as: leukotriene metabolism 
The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2016
01219892016

Papers overview

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2008
2008
Transcription factor and drug-metabolizing enzyme gene expression in lymphocytes from healthy human subjects.
We aimed to measure simultaneously the expression of drug-metabolizing enzymes (DME) and transcription factors (TF) with high… (More)
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2008
2008
Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation.
The hedgehog (Hh) pathway is required for many developmental processes, as well as for adult homeostasis. Although all known… (More)
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2007
2007
Influence of leukotriene gene polymorphisms on chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is increasingly viewed as an inflammatory condition of the sinonasal mucosa interacting with… (More)
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2007
2007
Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.
Sonic hedgehog (Shh) is a morphogen pivotal for development and tissue maintenance. Biological effects of Shh are mediated… (More)
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Review
2002
Review
2002
Genotype predictors of response to asthma medications.
The search for the genetic basis of asthma and other allergic diseases has identified many candidate genes. Some of these genes… (More)
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Review
2001
Review
2001
Antileukotrienes in asthma: present situation.
Leukotrienes are key mediators in asthma. Over the last 5 years, several antileukotrienes, including three receptor antagonists… (More)
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2000
2000
MK-886, a Leukotriene Biosynthesis Inhibitor, as an Activator of Ca Mobilization in Madin-Darby Canine Kidney (MDCK) Cells
The effect of 3-[1-(p-chlorobenzyl)-5-(isopropyl)-3-tert-butylthioindol-2-yl]-2, 2-dimethylpropanoic acid (MK-886), a leukotriene… (More)
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1999
1999
5-Lipoxygenase upregulation by dexamethasone in human mast cells.
In spite of intensive research, our understanding of the regulation of expression of 5-LO (the key enzyme in the leukotriene… (More)
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1993
1993
n-3 fatty acids and cysteinyl-leukotriene formation in humans in vitro, ex vivo, and in vivo.
In humans, dietary n-3 fatty acids ameliorate some chronic inflammatory diseases. In contrast, however, dietary n-3 fatty acids… (More)
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Review
1989
Review
1989
[Fish oil: clinical application possibilities].
Current interest in fish-oil stems in part from epidemiologic evidence gathered in eskimos. Due to a high proportion of fish in… (More)
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