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leucine biosynthetic process

Known as: leucine anabolism, leucine formation, leucine biosynthesis 
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid. [GOC:ai]

Topic mentions per year

Topic mentions per year

1954-2017
024619542016

Papers overview

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2009
2009
3-Methyl-1-butanol production in Escherichia coli: random mutagenesis and two-phase fermentation
Interest in producing biofuels from renewable sources has escalated due to energy and environmental concerns. Recently, the… (More)
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2007
2007
DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Deltasnf2 disruptant of Saccharomyces cerevisiae.
We previously found that SNF2, a gene encoding a transcription factor forming part of the SWI/SNF (switching/sucrose non… (More)
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2006
2006
Monitoring and modeling of the reaction dynamics in the valine/leucine synthesis pathway in Corynebacterium glutamicum.
The intracellular concentrations of the valine and leucine pathway intermediates in a Corynebacterium glutamicum strain were… (More)
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2006
2006
Kinetic and chemical mechanism of alpha-isopropylmalate synthase from Mycobacterium tuberculosis.
Mycobacterium tuberculosis alpha-isopropylmalate synthase (MtIPMS) catalyzes the condensation of acetyl-coenzyme A (AcCoA) with… (More)
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1998
1998
Structure and evolution of the leucine plasmids carried by the endosymbiont (Buchnera aphidicola) from aphids of the family Aphididae.
In all examined species of the family Aphididae, the bacterial endosymbiont Buchnera aphidicola carries a plasmid encoding the… (More)
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1997
1997
Putative evolutionary origin of plasmids carrying the genes involved in leucine biosynthesis in Buchnera aphidicola (endosymbiont of aphids).
An 8.5-kb plasmid encoding genes (leuABCD) involved in leucine biosynthesis and a small plasmid of 1.74 kb of yet unknown… (More)
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1996
1996
Neuronal metabolism of branched-chain amino acids: flux through the aminotransferase pathway in synaptosomes.
The metabolism of branched-chain amino acids (BCAAs) was studied in cortical synaptosomes. With [15N]leucine (1 mM) as precursor… (More)
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1984
1984
Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2.
Yeast LEU1 encodes the second enzyme in leucine biosynthesis. A 3.5-kilobase pair (kb) yeast genomic DNA fragment which… (More)
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1973
1973
Regulation of leucine biosynthesis in Bacillus subtilis.
The biosynthesis of alpha-isopropylmalate (alphaIPM) synthetase, IPM isomerase, and betaIPM dehydrogenase in Bacillus subtilis… (More)
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1962
1962
Control of isoleucine, valine, and leucine biosynthesis. I. Multivalent repression.
Repression of the formation of biosynthetic enzymes by the ultimate end product of their action has been shown to be an important… (More)
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