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The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli.
The leucine-responsive regulatory protein (Lrp) regulates the expression of more than 40 genes and proteins in Escherichia coli. Among the operons that are positively regulated by Lrp are operonsExpand
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A large family of bacterial activator proteins.
At least nine different bacterial proteins belong to the LysR family. The gene sequence for one of these proteins is presented here. Six others (Escherichia coli LysR, IlvY, CysB; SalmonellaExpand
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Compounds which serve as the sole source of carbon or nitrogen for Salmonella typhimurium LT-2.
About 600 compounds were screened as possible carbon or nitrogen sources for Salmonella typhimurium LT-2. About 100 utilizable compounds were found.
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Leucine-responsive regulatory protein controls the expression of both the pap and fan pili operons in Escherichia coli.
The methylation blocking factor gene (mbf) in Escherichia coli is required for specific methylation inhibition of two DNA GATC sites upstream of the papBA pilin promoter and transcriptionalExpand
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A consensus sequence for binding of Lrp to DNA.
Lrp (leucine-responsive regulatory protein) is a major regulatory protein involved in the expression of numerous operons in Escherichia coli. For ilvIH, one of the operons positively regulated byExpand
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Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine.
Lrp is a regulatory protein in Escherichia coli that increases expression of some operons and decreases expression of others. Mutations in Lrp were isolated on the basis of their effects on ilvIH,Expand
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Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH.
  • Q. Wang, J. Calvo
  • Biology, Medicine
  • Journal of molecular biology
  • 20 January 1993
Lrp (Leucine-responsive regulatory protein) has recently been recognized as a major regulatory protein that controls the expression of many operons in Escherichia coli. Footprinting and gelExpand
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The ilvIH operon of Escherichia coli is positively regulated.
The ilvIH operon of Escherichia coli (located near min 2) encodes acetohydroxyacid synthase III, an isozyme involved in branched-chain amino acid biosynthesis. A strain with lacZ fused to the ilvIHExpand
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Effects of nutrition and growth rate on Lrp levels in Escherichia coli.
Lrp (leucine-responsive regulatory protein) activates some Escherichia coli operons that function in anabolism and represses others involved in catabolism (for a review, see J. M. Calvo and R. G.Expand
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Transcriptional regulation of the ilv-leu operon of Bacillus subtilis.
We used primer extension and mutational analysis to identify a promoter upstream of ilvB, the first gene in the ilv-leu operon of Bacillus subtilis. Between the promoter and ilvB, there is a 482-bpExpand
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