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The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus.
Little is known about the mutational fitness effects associated with single-nucleotide substitutions on RNA viral genomes. Here, we used site-directed mutagenesis to create 91 single mutant clones ofExpand
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The Gypsy Database (GyDB) of mobile genetic elements: release 2.0
This article introduces the second release of the Gypsy Database of Mobile Genetic Elements (GyDB 2.0), a research project devoted to the evolutionary dynamics of viruses and transposable elements based on their phylogenetic classification (per lineage and protein domain). Expand
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A Small Microbial Genome: The End of a Long Symbiotic Relationship?
Intracellular bacteria are characterized by genome reduction. The 422,434–base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is ∼200 kilobases smaller thanExpand
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Learning how to live together: genomic insights into prokaryote–animal symbioses
Our understanding of prokaryote–eukaryote symbioses as a source of evolutionary innovation has been rapidly increased by the advent of genomics, which has made possible the biological study ofExpand
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High Diversity of the Viral Community from an Antarctic Lake
Shivering Viromes Despite its icy reputation, freshwater ponds and lakes do occur in Antarctica, and open freshwater can be found for a few brief weeks during the austral summer. The ecology of theseExpand
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Immunity and other defenses in pea aphids, Acyrthosiphon pisum
BackgroundRecent genomic analyses of arthropod defense mechanisms suggest conservation of key elements underlying responses to pathogens, parasites and stresses. At the center of pathogen-inducedExpand
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Side‐stepping secondary symbionts: widespread horizontal transfer across and beyond the Aphidoidea
To elucidate the co‐evolutionary relationships between phloem‐feeding insects and their secondary, or facultative, bacterial symbionts, we explore the distributions of three such microbes —Expand
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The genome sequence of Blochmannia floridanus: Comparative analysis of reduced genomes
  • R. Gil, F. Silva, +10 authors A. Moya
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 28 July 2003
Bacterial symbioses are widespread among insects, probably being one of the key factors of their evolutionary success. We present the complete genome sequence of Blochmannia floridanus, the primaryExpand
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Contribution of Taq polymerase-induced errors to the estimation of RNA virus diversity.
The genetic diversity of a vesicular stomatitis virus population was analysed by RT-PCR, cloning and sequencing of two approximately 500 nucleotide regions of the virus genome. PCR amplificationsExpand
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Genome Sequence of the Pea Aphid Acyrthosiphon pisum
The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.
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