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letrozole

Known as: Letrozol, letrozole [Chemical/Ingredient], Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis- 
A nonsteroidal inhibitor of estrogen synthesis with antineoplastic activity. As a third-generation aromatase inhibitor, letrozole selectively and… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (4)

Antineoplastic AgentsAromatase InhibitorsNitrilesTriazoles

Narrower (2)

CGS 20267Femara
Drug AllergyMammary NeoplasmsNCIt Antineoplastic Agent TerminologyPregnancy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Ovulation induction in polycystic ovary syndrome: Current options.
Highly Cited
2009
Highly Cited
2009
Use of aromatase inhibitors in poor-responder patients receiving GnRH antagonist protocols.
Review
2008
Review
2008
Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review.
Highly Cited
2008
Highly Cited
2008
Increased intrafollicular androgen levels affect human granulosa cell secretion of anti-Müllerian hormone and inhibin-B.
Review
2006
Review
2006
What do we know about the mechanisms of aromatase inhibitor resistance?
Highly Cited
2006
Highly Cited
2006
Leuprolide acetate plus aromatase inhibition for male breast cancer.
TO THE EDITOR: Approximately 1% of breast cancer occurs in male patients, yet little information is available on the optimal… 
Highly Cited
2005
Highly Cited
2005
Neurosteroid synthesis in the hippocampus: Role in synaptic plasticity
Highly Cited
2005
Highly Cited
2005
BIG 1-98: Randomized double-blind phase III study to evaluate letrozole (L) vs. tamoxifen (T) as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer
511 Background: L has been shown to be active in postmenopausal women with endocrine-responsive breast cancer for whom prior… 
Review
2003
Review
2003
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients
Highly Cited
2001
Highly Cited
2001
Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy
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