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lavendustin A

Known as: Benzoic acid, 5-[[(2, 5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy -, 5-(((2,5-Dihydroxyphenyl)methyl)((2-hydroxyphenyl)methyl)amino)-2-hydroxy Benzoic Acid, 5-amino-((N-2,5-dihydroxybenzyl)-N'-2-hydroxybenzyl)aminosalicylic acid 
A compound isolated from strains of Streptomyces griseolavendus that may exert antitumor activity by inhibition of protein tyrosine kinase and… Expand
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Interleukin (IL)-1β is a proinflammatory cytokine implicated in various pathophysiological conditions of the CNS involving NMDA… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Phytoestrogens, including genistein and other inhibitors of tyrosine kinases (TKs), inhibit specific steroidogenic… Expand
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Highly Cited
2002
Highly Cited
2002
Abstract Outbred CD-1 mice were treated neonatally on Days 1–5 with the phytoestrogen, genistein (1, 10, or 100 μg per pup per… Expand
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Highly Cited
2001
Highly Cited
2001
The “metabolic cocktail” comprising glucose-insulin-potassium administrated at reperfusion reduces infarct size in the in vivo… Expand
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Highly Cited
2000
Highly Cited
2000
The metabolic cocktail of glucose-insulin-potassium (GIK) has been shown to reduce mortality in humans and reduce infarct size in… Expand
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Highly Cited
1999
Highly Cited
1999
Although it is recognized that late preconditioning (PC) results from upregulation of cardioprotective genes, the specific… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract Angiotensin II (AngII) is coupled to several important intracellular signaling pathways, and increases intracellular Ca2… Expand
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Highly Cited
1995
Highly Cited
1995
  • D. Hu, T. Fan
  • British journal of pharmacology
  • 1995
  • Corpus ID: 28070586
1 Vascular endothelial growth factor (VEGF) is a heparin‐binding angiogenic factor which specifically acts on endothelial cells… Expand
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Highly Cited
1991
Highly Cited
1991
LONG-TERM potentiation (LTP) in the hippocampus is thought to contribute to memory formation. In the Ca1 region, LTP requires the… Expand
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Highly Cited
1989
Highly Cited
1989
A potent tyrosine kinase inhibitor, lavendustin A [1], has been isolated from a butyl acetate extract of Streptomyces… Expand
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