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lavendustin A

Known as: Benzoic acid, 5-[[(2, 5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy -, 5-(((2,5-Dihydroxyphenyl)methyl)((2-hydroxyphenyl)methyl)amino)-2-hydroxy Benzoic Acid, 5-amino-((N-2,5-dihydroxybenzyl)-N'-2-hydroxybenzyl)aminosalicylic acid 
A compound isolated from strains of Streptomyces griseolavendus that may exert antitumor activity by inhibition of protein tyrosine kinase and… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Enzyme InhibitorsPhenols
NCIt Antineoplastic Agent TerminologyReceptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes.
Highly Cited
2002
Highly Cited
2002
Tyrosine dephosphorylation underlies DHPG-induced LTD
Highly Cited
2002
Highly Cited
2002
Acute and chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells.
BACKGROUND Phytoestrogens, including genistein and other inhibitors of tyrosine kinases (TKs), inhibit specific steroidogenic… 
2001
2001
Study of cytoskeletal changes induced by okadaic acid in BE(2)-M17 cells by means of a quantitative fluorimetric microplate assay.
Highly Cited
1999
Highly Cited
1999
Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro
Highly Cited
1999
Highly Cited
1999
Angiotensin II stimulation of Ca2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002
Abstract Angiotensin II (AngII) is coupled to several important intracellular signaling pathways, and increases intracellular Ca2… 
Highly Cited
1997
Highly Cited
1997
Activation of ICAM-1 promoter by lysophosphatidylcholine: possible involvement of protein tyrosine kinases.
Highly Cited
1996
Highly Cited
1996
Tyrosine Kinase Is Required for Long-Term Depression in the Cerebellum
Highly Cited
1995
Highly Cited
1995
Suppression of VEGF‐induced angiogenesis by the protein tyrosine kinase inhibitor, lavendustin A
1 Vascular endothelial growth factor (VEGF) is a heparin‐binding angiogenic factor which specifically acts on endothelial cells… 
Highly Cited
1989
Highly Cited
1989
Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus.
A potent tyrosine kinase inhibitor, lavendustin A [1], has been isolated from a butyl acetate extract of Streptomyces… 
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