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lavendustin A

Known as: Benzoic acid, 5-[[(2, 5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxy -, 5-(((2,5-Dihydroxyphenyl)methyl)((2-hydroxyphenyl)methyl)amino)-2-hydroxy Benzoic Acid, 5-amino-((N-2,5-dihydroxybenzyl)-N'-2-hydroxybenzyl)aminosalicylic acid 
A compound isolated from strains of Streptomyces griseolavendus that may exert antitumor activity by inhibition of protein tyrosine kinase and… 
National Institutes of Health

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4 relations

Broader (2)

Enzyme InhibitorsPhenols
NCIt Antineoplastic Agent TerminologyReceptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Genistein directly inhibits native and recombinant NMDA receptors
2009
2009
Tyrosine kinase-independent inhibition by genistein on spermatogenic T-type calcium channels attenuates mouse sperm motility and acrosome reaction.
2008
2008
Role of different protein tyrosine kinases in fMLP-induced neutrophil transmigration.
2003
2003
Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.
Compounds in the lavendustin A series have been shown to inhibit both protein-tyrosine kinases (PTKs) and tubulin polymerization… 
2000
2000
Direct inhibition of glycine receptors by genistein, a tyrosine kinase inhibitor
Highly Cited
1999
Highly Cited
1999
Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro
1996
1996
Chloride efflux during the progesterone-initiated human sperm acrosome reaction is inhibited by lavendustin A, a tyrosine kinase inhibitor.
Previous studies showed that progesterone (P) can initiate the mammalian sperm acrosome reaction (AR) in vitro and that a sperm… 
Review
1995
Review
1995
Isolation and biological activities of signal transduction inhibitors from microorganisms and plants.
1993
1993
Non-amine based analogues of lavendustin A as protein-tyrosine kinase inhibitors.
The fermentation product lavendustin A (1) is a protein-tyrosine kinase (PTK) inhibitor whose active pharmacophore has previously… 
1992
1992
Effects of insulin and tyrosine kinase inhibitor on ion transport in the alveolar cell of the fetal lung.
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