lactacystin
National Institutes of Health
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Although tumor necrosis factor (TNF)-α is implicated in numerous cardiac pathologies, the intracellular events leading to its…
The multicatalytic protease complex or proteasome is a fundamental nonlysosomal tool that the cell uses to process or degrade…
Insulin receptor substrate (IRS) proteins are important intracellular molecules that mediate insulin receptor tyrosine kinase…
A selective, irreversible inhibitor of proteasome function, lactacystin (1) is an important experimental tool in cell biology. An…
Intercellular communication may be modulated by the rather rapid turnover and degradation of gap junction proteins, since many…