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jatrophone

Known as: 2,3,7,8-tetrahydro-2,5,8,8,12-pentamethyl-3 alpha, 6-epoxy-3 alphaH-cyclopentacyclododecin-4,11-dione 
National Institutes of Health

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Broader (1)

Diterpenes

Papers overview

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2020
2020
Inhibition of glioma cell viability by jatrophone via NF-κB down-regulation and apoptosis inhibitor up-regulation
Introduction: The present study evaluated the pro-survival signaling pathway inhibition potential of jatrophone in glioblastoma… 
2018
2018
Neuroprotective Effects of Ferruginol, Jatrophone, and Junicedric Acid Against Amyloid-β Injury in Hippocampal Neurons.
Soluble amyloid-β (Aβ) oligomers have been recognized as early neurotoxic intermediates with a key role in the synaptic… 
2018
2018
Correction: The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
[This corrects the article DOI: 10.1371/journal.pone.0189864.]. 
2010
2010
A new macrocyclic diterpenoid from Jatropha multifida
A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the… 
2006
2006
Quantitative determination of jatrophone in "cachaça" prepared with Jatropha elliptica.
A method for sample preparation and analysis by high performance liquid chromatography with UV detection (HPLC-UV) was developed… 
1999
1999
Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.
Most cases of cystic fibrosis (CF), a common inherited disease of epithelial cell origin, are caused by the deletion of Phe508… 
1983
1983
Study of the binding of jatrophone to Escherichia coli s‐ribonucleic acid
1981
1981
On the interaction between jatrophone and DNA
1976
1976
[Studies on pharmacokinetics and biotransformation of ipratropiumbromide in man (author's transl)].
Studies into the human pharmacokinetics of (8r)-3alpha-hydroxy-8-isopropyl-1 alphaH, 5 alphaH-tropanium-bromide- (+/-)-tropate… 
1973
1973
Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase.
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