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jatrophone

Known as: 2,3,7,8-tetrahydro-2,5,8,8,12-pentamethyl-3 alpha, 6-epoxy-3 alphaH-cyclopentacyclododecin-4,11-dione 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Diterpenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
Metastatic breast cancer is the leading cause of worldwide cancer-related deaths among women. Triple negative breast cancers… 
2013
2013
Evaluation of Jatropha isabelli natural products and their synthetic analogs as potential antimalarial therapeutic agents.
Highly Cited
2007
Highly Cited
2007
Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug "yagua rova" (Jatropha isabelli).
2005
2005
Three New Jatrophone-Type Diterpenoids from Euphorbia helioscopia
Euphorbia helioscopia 
Highly Cited
2001
Highly Cited
2001
Release of intermediate reactive hydrogen peroxide by macrophage cells activated by natural products.
By determining the hydrogen peroxide (H2O2) released in cultures of peritoneal macrophage cells from Swiss mice, we evaluated the… 
2001
2001
A minor coumarino-lignoid from Jatropha gossypifolia.
Highly Cited
1996
Highly Cited
1996
Antiprotozoal activity of Jatrogrossidione from Jatropha grossidentata and Jatrophone from Jatropha isabellii
The activity of jatrogrossidione, the main diterpene of Jatropha grossidentata and jatrophone from Jatropha isabellii was… 
Highly Cited
1983
Highly Cited
1983
Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics.
GSH plays an important role in cellular defense against a wide variety of toxic electrophiles via the formation of thioether… 
Highly Cited
1981
Highly Cited
1981
Additions and Corrections - A Strategy for the Total Synthesis of Jatrophone: Synthesis of Normethyljatrophone
Highly Cited
1976
Highly Cited
1976
Structure and stereochemistry of jatrophone, a novel macrocyclic diterpenoid tumor inhibitor.
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