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ipilimumab

Known as: MOAB-CTLA-4, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, monoclonal antibody CTLA-4 
A recombinant human immunoglobulin (Ig) G1 monoclonal antibody directed against the human T-cell receptor cytotoxic T-lymphocyte-associated antigen 4… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
This article has been accepted for publication and undergone full peer review but has not been through the copyediting… 
2017
2017
Programmed death 1 receptor (PD-1) inhibitors, such as nivolumab, are effective in the treatment of advanced and metastatic… 
2016
2016
514 Background: Durable benefit with CTLA4 or PD1 blockade associates with high somatic mutation burden in melanoma and lung… 
2015
2015
9055 Background: PD-1 antibodynivolumab was administered with/without a multi-peptide vaccine to 126 patients (pts) with… 
2015
2015
We present a patient who developed granuloma annulare during ipilimumab therapy. Many adverse events of ipilimumab therapy are… 
2015
2015
In the first randomized trial to compare FDA-approved immune checkpoint inhibitors as first-line therapy for patients with… 
Review
2013
Review
2013
Ipilimumab is an anticytotoxic T lymphocyte antigen-4 (CTLA-4) monoclonal antibody that attenuates negative signaling from CTLA-4… 
2012
2012
Long-standing efforts to develop drugs that target MEKs could soon come to fruition, moving the frontier to how best to combine… 
2012
2012
Ipilimumab (commercial name YervoyTM, Bristol-Myers Squibb, Princeton, NJ) was approved on March 25, 2011 by the US Food and Drug… 
2011
2011
With recent successes of immunotherapies and targeted drugs, melanoma has become one of the most dynamic areas of anticancer drug…