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ipilimumab
Known as:
MOAB-CTLA-4
, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody
, monoclonal antibody CTLA-4
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A recombinant human immunoglobulin (Ig) G1 monoclonal antibody directed against the human T-cell receptor cytotoxic T-lymphocyte-associated antigen 4…
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National Institutes of Health
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Related topics
Related topics
16 relations
10 ML ipilimumab 5 MG/ML Injection
10 ML ipilimumab 5 MG/ML Injection [Yervoy]
CP-675,206
CTLA4 protein, human
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Narrower (3)
BMS-734016
MDX-010
Yervoy
Broader (1)
Monoclonal Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Baseline neutrophil to lymphocyte ratio combined with serum LDH level associated with outcome of nivolumab immunotherapy in a Japanese advanced melanoma population
Y. Fujisawa
,
K. Yoshino
,
+13 authors
S. Matsushita
2018
Corpus ID: 261283342
This article has been accepted for publication and undergone full peer review but has not been through the copyediting…
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2017
2017
Management of dermatological adverse events during nivolumab treatment
M. Słowińska
,
A. Maciąg
,
Natalia Rozmus
,
E. Paluchowska
,
W. Owczarek
2017
Corpus ID: 55331731
Programmed death 1 receptor (PD-1) inhibitors, such as nivolumab, are effective in the treatment of advanced and metastatic…
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2016
2016
Mutation burden and tumor neoantigens in RCC patients (pts) treated with nivolumab.
M. Voss
,
M. Hellmann
,
+6 authors
R. Motzer
2016
Corpus ID: 78597133
514 Background: Durable benefit with CTLA4 or PD1 blockade associates with high somatic mutation burden in melanoma and lung…
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2015
2015
Survival, biomarker, and toxicity analysis of nivolumab (NIVO) in patients that progressed on ipilimumab (IPI).
J. Weber
,
G. Gibney
,
+7 authors
M. Schell
2015
Corpus ID: 77690335
9055 Background: PD-1 antibodynivolumab was administered with/without a multi-peptide vaccine to 126 patients (pts) with…
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2015
2015
Granuloma Annulare in the Setting of Ipilimumab Therapy
Haselden Vn
,
Ritva Vyas
,
H. Koon
,
M. Gerstenblith
2015
Corpus ID: 20269259
We present a patient who developed granuloma annulare during ipilimumab therapy. Many adverse events of ipilimumab therapy are…
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2015
2015
Pembrolizumab superior to ipilimumab in melanoma.
Cancer Discovery
2015
Corpus ID: 7226013
In the first randomized trial to compare FDA-approved immune checkpoint inhibitors as first-line therapy for patients with…
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Review
2013
Review
2013
Key issues in the management of gastrointestinal immune-related adverse events associated with ipilimumab administration
M. Sznol
,
M. Callahan
,
Jianda Yuan
,
J. Wolchok
2013
Corpus ID: 55466406
Ipilimumab is an anticytotoxic T lymphocyte antigen-4 (CTLA-4) monoclonal antibody that attenuates negative signaling from CTLA-4…
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2012
2012
New class of kinase inhibitors poised to join the anticancer arsenal
Alisa Opar
Nature reviews. Drug discovery
2012
Corpus ID: 5632297
Long-standing efforts to develop drugs that target MEKs could soon come to fruition, moving the frontier to how best to combine…
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2012
2012
Ipilimumab: Developmental History, Clinical Considerations, and Future Perspectives
M. Postow
,
J. Wolchok
,
Bristol-Myers Squibb
,
P. Robins
2012
Corpus ID: 78244532
Ipilimumab (commercial name YervoyTM, Bristol-Myers Squibb, Princeton, NJ) was approved on March 25, 2011 by the US Food and Drug…
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2011
2011
Dual fronts poised to transform melanoma therapy
Asher Mullard
Nature reviews. Drug discovery
2011
Corpus ID: 30757872
With recent successes of immunotherapies and targeted drugs, melanoma has become one of the most dynamic areas of anticancer drug…
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