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intracellular signal transduction

Known as: intracellular signaling cascade, intracellular signaling chain 
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
The vast majority of proteins that a cell secretes or displays on its surface first enter the endoplasmic reticulum (ER), where… Expand
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Highly Cited
2011
Highly Cited
2011
Effective prediction of the direction of signal flow in an interaction network enables modeling of signaling dynamics and… Expand
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Review
2007
Review
2007
The endoplasmic reticulum (ER) responds to the accumulation of unfolded proteins in its lumen (ER stress) by activating… Expand
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Highly Cited
2006
Highly Cited
2006
Tissue-type plasminogen activator (tPA), a serine protease well known for generating plasmin, has been demonstrated to induce… Expand
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Review
2005
Review
2005
H2O2 is a reactive oxygen species that has drawn much interest because of its role as a second messenger in receptor-mediated… Expand
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Review
2004
Review
2004
Protein phosphorylation and dephosphorylation play a major role in intracellular signal transduction activated by extracellular… Expand
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Review
2002
Review
2002
Transforming growth factor-beta (TGF-beta) superfamily members regulate a plethora of developmental processes, and disruption of… Expand
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Review
2001
Review
2001
Drosophila Toll protein is a transmembrane receptor whose function is to recognize the invasion of microorganisms as well as to… Expand
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Highly Cited
2000
Highly Cited
2000
A central feature of drugs of abuse is to induce gene expression in discrete brain structures that are critically involved in… Expand
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Highly Cited
1993
Highly Cited
1993
The transcription of genes encoding soluble proteins that reside in the endoplasmic reticulum (ER) is induced when unfolded… Expand
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