integrin alpha4beta7

Known as: Integrin a4b7, LPAM-1 adhesion molecule, lymphocyte-Peyer's patch adhesion molecule 
Integrin alpha4/beta7 is a protein complex comprised of a heterodimer of integrin alpha4 and integrin beta7. This complex plays a role in cell-cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
0102019762017

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Highly Cited
2008
Highly Cited
2008
BACKGROUND & AIMS Selective blockade of lymphocyte-vascular endothelium interactions in the gastrointestinal tract is a promising… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Selective blockade of interactions between leukocytes and vascular endothelium in the gut is a promising strategy for… (More)
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Highly Cited
2002
Highly Cited
2002
The integrin alpha4beta7 binds to MAdCAM-1 and contributes to homing of lymphocytes to gut and other mucosal tissues. In humans… (More)
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Highly Cited
2002
Highly Cited
2002
Effector and memory T cells can be subdivided based on their ability to traffic through peripheral tissues such as inflamed skin… (More)
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Highly Cited
2001
Highly Cited
2001
CCR7, along with L-selectin and LFA-1, mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV… (More)
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Highly Cited
1997
Highly Cited
1997
Lymphocyte homing to normal tissues and recruitment to inflammatory tissue sites are controlled, in part, by the selective… (More)
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Highly Cited
1997
Highly Cited
1997
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an adhesion protein expressed on endothelium in mucosal tissues that has… (More)
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Highly Cited
1995
Highly Cited
1995
Of the several families of adhesion receptors involved in leukocyte-endothelial cell interactions, only the selectins have been… (More)
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Highly Cited
1995
Highly Cited
1995
Circulating lymphocytes home to the mucosal lymphoid organs, Peyer's patches (PP), through high endothelial venules (HEV). In… (More)
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Highly Cited
1993
Highly Cited
1993
The mucosal vascular addressin, MAdCAM-1, is an immunoglobulin superfamily adhesion molecule for lymphocytes that is expressed by… (More)
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