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integrin alpha4beta7

Known as: Integrin a4b7, LPAM-1 adhesion molecule, lymphocyte-Peyer's patch adhesion molecule 
Integrin alpha4/beta7 is a protein complex comprised of a heterodimer of integrin alpha4 and integrin beta7. This complex plays a role in cell-cell… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell AdhesionCell Adhesion MoleculesCell-Cell Adhesion ProcessCell-Matrix Junction

Broader (1)

Integrins

Papers overview

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1998
1998
The β7 integrin gene (Itgb-7) promoter is responsive to TGF-β1: defining control regions
Abstract The β7 integrins LPAM-1 (α4β7) and M290 (αEβ7) mediate the homing of lymphocytes to gut-associated lymphoid tissue, and… 
Highly Cited
1997
Highly Cited
1997
Topographic distribution of homing receptors on B and T cells in human gut-associated lymphoid tissue: relation of L-selectin and integrin alpha 4 beta 7 to naive and memory phenotypes.
In mice, integrin alpha 4 beta 7 is the main receptor used by lymphocytes that home to the Peyer's patches, although L-selectin… 
Highly Cited
1997
Highly Cited
1997
A cyclic hexapeptide is a potent antagonist of alpha 4 integrins.
The alpha 4 integrins mediate leukocyte adhesion to specific counter-receptors, including vascular cell adhesion molecule-1 (VCAM… 
Highly Cited
1996
Highly Cited
1996
Distribution of β7 integrins in human intestinal mucosa and organized gut‐associated lymphoid tissue
Two alternative integrins involved in mucosal homing (α4β7) or epithelial retention (αEβ7) of lymphocytes were examined in the… 
Highly Cited
1995
Highly Cited
1995
L-selectin and alpha 4 beta 7 integrin homing receptor pathways mediate peripheral lymphocyte traffic to AKR mouse hyperplastic thymus.
Before the development of thymic lymphoma, AKR mice undergo a striking lymphoid hyperplasia of the thymic medulla. We have… 
1995
1995
Expression of the Human Mucosal Lymphocyte Antigen, HML‐1, by T Cells Activated with Mitogen or Specific Antigen In Vitro
Expression of the human mucosal lymphocyte antigen, HML‐1 (CD103), recently identified as a novel äEβ7 integrin, was studied on… 
1993
1993
Expression of adhesion molecules by human decidual large granular lymphocytes.
This study has examined the expression of adhesion molecules by uterine-specific CD56bright CD16-CD3- large granular lymphocytes… 
1993
1993
Physical association of CD5 and the T cell receptor/CD3 antigen complex on the surface of human T lymphocytes
The physical association of CD5 and the Tcell antigen receptor (TcR)/CD3 complex on the surface of intact human lymphocytes was… 
Highly Cited
1992
Highly Cited
1992
A family of beta 7 integrins on human mucosal lymphocytes.
The heterodimeric protein complex recognized by the human mucosal lymphocyte 1 (HML-1) monoclonal antibody is expressed on 95% of… 
Highly Cited
1991
Highly Cited
1991
Expression and regulation of beta 7(beta p) integrins on mouse lymphocytes: relevance to the mucosal immune system.
A mouse lymphocyte surface molecule which is selectively expressed by mucosal T cells and detected with the monoclonal antibody… 
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